338957-82-7

Usage

Structure

Acetamide derivative with a thiazole ring and a phenylsulfanyl group (the compound has a specific structure that includes a five-membered ring with a sulfur atom and a phenyl group attached to a sulfanyl sulfur)

Pharmaceutical applications

Potential uses (the compound has potential for development and use in pharmaceuticals due to its structural features and functional groups)

Safety hazards

May have health and safety hazards associated with its handling and use (it is important to handle the compound with care and follow proper safety protocols to avoid potential risks)

Upstream product

• 2010-06-2 2-Amino-4-phenylthiazole 
• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 

Relevant academic research and scientific papers

Synthesis and free radical scavenging activity of 2-alkyl/arylchalcogenyl-N-(4-aryl-1,3-thiazol-2-yl)acetamide compounds

The synthesis of a new series of organochalcogen-derivatives, 2-alkyl/arylchalcogenyl-N-(4-aryl-1,3-thiazol-2-yl)acetamides 5a-r, provided products in satisfactory yields, which varied from 42% to 95%. All these novel compounds were screened for their in vitro free radical scavenging activity against 2,2-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals. Compounds 5 (m, h, i, f, q, g, l, c, n) were effective scavengers against the ABTS radical species but less effective on scavenging the DPPH radical, indicating that the antioxidant effect of these compounds were related to protonated radical scavenger activity.