339016-22-7Relevant academic research and scientific papers
Copper-mediated coupling of aminopurines and aminopyrimidines with arylboronic acids
Joshi, Ramesh A.,Patil, Pratap S.,Muthukrishnan,Ramana,Gurjar, Mukund K.
, p. 195 - 197 (2004)
Selective N-arylation of aminopurines and aminopyrimidines 1-3 with arylboronic acids 4-6 was explored using copper(II) acetate and the corresponding N-arylated purine and pyrimidine derivatives 7-15 were obtained in moderate to good yields.
Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents
Kim, Woochan,Kang, Jung-Ah,Park, Minji,Jeong, Pyeong-Hwa,Kim, Yoon Jun,Cho, Yuri,Park, Sung-Gyoo,Kim, Yong-Chul
, p. 5500 - 5518 (2021)
Core assembly modulators of viral capsid proteins have been developed as an effective treatment of chronic hepatitis B virus (HBV) infection. In this study, we synthesized novel potent pyrimidine derivatives as core assembly modulators, and their antivira
