339018-41-6Relevant academic research and scientific papers
Novel vanillin derivatives containing a 1,3,4-thiadiazole moiety as potential antibacterial agents
Cai, Hui,Gan, Xiuhai,Li, Shaoyuan,Song, Baoan,Wu, Qiong,Yuan, Ting
supporting information, (2020/03/24)
In this study, thirty-four novel vanillin derivatives containing a 1,3,4-thiadiazole structure were obtained and their antibacterial activities were evaluated. The results indicate that most of the title compounds displayed inhibitory effects on Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas oryzae pv. oryzicola (Xoc). Among them, compound 29 exhibited excellent antibacterial activities against Xoo and Xoc in vitro, with the EC50 values of 3.14 and 8.83 μg/mL, respectively, much superior to thiodiazole copper (87.03 and 108.99 μg/mL) and bismerthiazol (67.64 and 79.26 μg/mL). Under greenhouse condition, the protective efficiency of compound 29 against rice bacterial leaf blight was 49.34%, and curative efficiency was 40.96%. In addition, compound 29 can reduce the exopolysaccharides production of Xoo, increase the permeability of cell membrane and damage cell membrane.
Synthesis and herbicidal activities of 2-cyano-3-benzylaminoacrylates containing thiazole moiety
Wang, Tingting,Bing, Guifang,Zhang, Xin,Qin, Zhenfang,Yu, Haibo,Qin, Xue,Dai, Hong,Miao, Wenke,Wu, Shanshan,Fang, Jianxin
supporting information; experimental part, p. 3348 - 3351 (2010/07/16)
Two series of novel 2-cyano-3-benzylaminoacrylates containing long-chain thiazole ring moiety were synthesized as herbicidal inhibitors of photosystem II (PS II) electron transportation. Their structures were confirmed by 1H NMR and elemental a
