33941-95-6Relevant academic research and scientific papers
Efficient ruthenium-catalyzed transfer hydrogenation/hydrogenation of 1,3-cycloalkanediones to 1,3-cycloalkanediols using microwave heating
Leijondahl, Karin,Fransson, Ann-Britt L.,Baeckvall, Jan-E.
, p. 8622 - 8625 (2007/10/03)
A number of 1,3-cycloalkanediones were efficiently reduced to the corresponding diols in good yield by the use of a ruthenium catalyst, 2-propanol, and hydrogen gas under microwave heating.
THE CONFORMATIONAL EQUILIBRIUM OF 1,3-DICHLORO-5-METHYLCYCLOHEXANE
Dosen-Micovic, Ljiljana,Jeremic, Dragoslav,Allinger, Norman L.
, p. 3455 - 3461 (2007/10/02)
Two of the stereoisomers of the title compound were prepared and their dipole moments were measured.For the r-1,c-3-dichloro-t-5-methylcyclohexane, the free energy difference between conformers with axial-axial (aa) and equatorial-equatorial (ee) chlorines was measured by a variable temperature NMR method, and the value found was 1.3+/-0.2 kcal mol-1 (in acetone) favoring the latter.Molecular mechanics studies show that the solvation energy and the electrostatics are of major importance in understanding this equilibrium.Calculations show the effect of the methyl group is essentially additive, and give for cis-1,3-dichlorocyclohexane itself eeaa ΔH +3.0 kcal mol-1 (acetone).
