33944-94-4Relevant academic research and scientific papers
New ketone homoenolate anion equivalents derived from (alkenyl)pentamethyl phosphoric triamides
Grison, Claude,Thomas, Antoine,Coutrot, Frédéric,Coutrot, Philippe
, p. 2101 - 2123 (2007/10/03)
Lithiated ambident anions derived from (1-alkyl-2-propenyl)- or (1-phenyl-2-propenyl)-pentamethyl phosphoric triamides undergo regioselectively γ-reaction with various alkylating reagents and isobutyraldehyde. Further hydrolysis of adducts releases the ketone under acid conditions. Number of synthetic applications clearly show the ketone homoenolate behaviour of these new carbanions.
Stepwise controlled reduction of α-oxoketene dithioacetals with Zn/ZnCl2-TMEDA in ethanol
Yadav, K. Mallik,Suresh, Joghee R.,Patro, Balaram,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 4679 - 4686 (2007/10/03)
α-Oxoketene dithioacetals 1 are shown to undergo highly selective conjugate reduction with Zn/ZnCl2-TMEDA in refluxing ethanol under controlled reaction conditions to afford β-methylthiomethylene ketones 6, β-methylthioketones 7 and the completely desulphurized α-methylketones 8 in sequential manner.
Regio- and chemoselective conjugate 1,4-reduction of α-oxoketene dithioacetals with sodium borohydride and sodium cyanoborohydride
Srinivasa Rao,Chakrasali,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 2195 - 2204 (2007/10/02)
Theα-oxoketene dithioacetals 1 are shown to undergo conjugate 1,4-reduction in highly regio- and chemoselective manner with sodium borohydride in acetic acid to afford the corresponding β-oxodithioacetals 5 in good yields. These results have been rational
