339555-43-0

Upstream product

• 1628-89-3 2-methoxypyridine 
• 104-15-4 toluene-4-sulfonic acid 
• 339555-40-7 tert-butyl (3S)-3-{benzyl[(1R)-1-phenylethyl]amino}-3-(6-methoxypyridin-3-yl)propanoate 
• 13472-85-0 2-methoxy-5-bromopyridine 
• 67000-01-5 methyltertbutyl ether 

Relevant academic research and scientific papers

COMPOSITION AND METHODS FOR TREATING CHRONIC KIDNEY DISEASE

This invention relates to the treatment of chronic kidney disease, including diabetic nephropathy, focal segmental glomerulosclerosis (FSGS), nephrotic syndrome, non-diabetic chronic kidney disease, renal fibrosis or acute kidney injury by the administrat

COMPOSITIONS AND METHODS FOR TREATING CANCER

The instant invention provides a method of treating a cancer selected from the group consisting of non-small cell lung cancer and breast cancer with an mTOR inhibitor and an αvβ3 integrin antagonist, wherein the mTOR inhibitor is ridaforolimus, everolimus, temsirolimus or a combination thereof.

Alpha V integrin receptor antagonists

The present invention relates to novel imidazolidinone derivatives thereof, their synthesis, and their use as αv integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors αvβ3 and/or