339570-92-2

Upstream product

• 197505-16-1 (1S,2S,3R)-2-Benzyloxy-3-trifluoromethanesulfonyloxy-cyclohexanecarboxylic acid methyl ester 
• 339570-86-4 (2S,3R,4S)-3-(3-hydroxy-2-allyl-1-oxo-5-hexenyl)-4-benzyl-2-oxazolidinone 
• 339570-90-0 ((2R,3R,4S)-4-Benzyloxy-3-methoxymethoxy-2,5-dimethyl-hexyloxy)-tert-butyl-dimethyl-silane 
• 339570-89-7 (2R,3R,4S)-4-(benzyloxy)-1-[(tert-butyldimethylsilyl)oxy]-2,5-dimethyl-3-hexanol 
• 339570-87-5 (1R,2R,4S)-4-benzyl-3-[(2-hydroxy-3-cyclohexen-1-yl)carbonyl]-2-oxazolidinone 
• 339570-88-6 (2R,4S)-4-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-2,5-dimethyl-hexan-3-one 
• 197505-17-2 (1S,2S,3S)-3-azido-2-benzyloxycyclohexanecarboxylic acid methyl ester 
• 197505-15-0 (1R,5S,8S)-8-benzyloxy-7-oxa-bicyclo[3.2.1]-octan-6-one 
• 197505-14-9 (1R,2S,5S,8S)-8-hydroxy-2-iodo-7-oxa-bicyclo[3.2.1]-octan-6-one 
• 159517-29-0 (1S,2R)-2-hydroxy-3-cyclohexanecarboxylic acid 
• 174759-97-8 (1R,5S,8S)-8-hydroxy-7-oxa-bicyclo[3.2.1]-octan-6-one 
• 158195-43-8 acetic acid (6S)-(10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-(1R)-cyclohex-2-enyl ester 
• 126587-67-5 (2R,3S,4S)-4-(benzyloxy)-1-<(tert-butyldimethylsilyl)oxy>-2,5-dimethyl-3-hexanol 
• 197505-19-4 (1S,2S,3S)-3-azido-2-benzyloxycyclohexanecarboxylic acid 

Downstream Products

• 339570-95-5 C₇₀H₉₅N₅O₁₇ 
• 339570-96-6 cyclo-[N-(tert-butyloxycarbonyl)-O-[[N-[(2S,3R,4S)-4-[(1S,2S,3S)-3-amino-2-benzyloxycyclohexanecarbonyl]oxy-3-(methoxymethoxy)-2,5-dimethylhexanoyl]-L-leucyl]-L-prolyl-N,O-dimethyl-L-tyrosyl]-L-threonyl] 
• 339570-94-4 (1S,2R,3R)-1-isopropyl-2-(methoxymethoxy)-3-methylbutanoic benzyl ester, ester with (1S,2S,3S)-3-azido-2-benzyloxycyclohexanecarboxylate 
• 1026914-48-6 (1S,2S,3S)-3-Amino-2-benzyloxy-cyclohexanecarboxylic acid (1S,2R,3S)-3-benzyloxycarbonyl-1-isopropyl-2-methoxymethoxy-butyl ester 

Relevant academic research and scientific papers

Total synthesis of a conformationally constrained didemnin B analog

The total synthesis of a didemnin B analogue containing a conformationally constrained replacement for the isostatine moiety is reported. Synthetic highlights include an improved preparation of 2-hydroxy-3-cyclohexenecarboxylic acid and a new strategy for accessing the macrocycle.