3397-29-3 Usage
Uses
Used in Medical Research:
PHT-GLY-OSU is used as a research tool for studying the interactions between different chemical compounds and their effects on biological systems. The system's unique properties allow for the exploration of new pathways and mechanisms in medical and pharmaceutical applications.
Used in Materials Science:
PHT-GLY-OSU is utilized as a component in the development of new materials with specific properties, such as enhanced strength, flexibility, or chemical resistance. The combination of phenol, glycine, and osmium tetroxide can lead to the creation of novel materials with potential applications in various industries.
Used in Industrial Chemistry:
PHT-GLY-OSU is employed as a reactant or catalyst in various chemical processes and reactions within the industrial chemistry sector. The system's unique reactivity and properties can contribute to the production of new chemicals, plastics, or pharmaceuticals, enhancing the efficiency and effectiveness of industrial processes.
Used in Tissue Staining for Histology:
PHT-GLY-OSU is used as a staining agent in histology to provide contrast and detail in tissue samples. The osmium tetroxide component, known for its staining capabilities, can enhance the visualization of cellular structures and features when combined with phenol and glycine in the PHT-GLY-OSU system.
Used in the Production of Chemicals, Plastics, and Pharmaceuticals:
PHT-GLY-OSU is utilized as a key component in the synthesis of various chemicals, plastics, and pharmaceuticals. The system's versatility and reactivity allow for the development of new products with improved properties and performance, contributing to advancements in these industries.
Check Digit Verification of cas no
The CAS Registry Mumber 3397-29-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,9 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3397-29:
(6*3)+(5*3)+(4*9)+(3*7)+(2*2)+(1*9)=103
103 % 10 = 3
So 3397-29-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H10N2O6/c17-10-5-6-11(18)16(10)22-12(19)7-15-13(20)8-3-1-2-4-9(8)14(15)21/h1-4H,5-7H2
3397-29-3Relevant academic research and scientific papers
Acyl, N-Protected α-Aminoacyl, and Peptidyl Derivatives as Prodrug Forms of the Alcohol Deterrent Agent Cyanamide
Kwon, Chul-Hoon,Nagasawa, Herbert T.,DeMaster, Eugene G.,Shirota, Frances N.
, p. 1922 - 1929 (2007/10/02)
Cyanamide , a potent aldehyde dehydrogenase (AlDH) inhibitor that is used therapeutically as an alcohol deterrent agent, is known to be rapidly metabolized and excreted in the urine as acetylcyanamide (1). On the basis of our observation that 1 is deacetylated to cyanamide in vivo, albeit very slightly, thereby serving as a precursor or prodrug form of the latter, several acyl derivatives of cyanamide were synthesized specifically as prodrugs, including benzoylcyanamide (2), pivaloylcyanamide (3), and 1-adamantoylcyanamide (4), as well as long- and medium-chain fatty acyl derivatives such as palmitoyl- (6), stearoyl- (7), and n-butyrylcyanamide (5). N-Protected α-aminoacyl and peptidyl derivatives of cyanamide were also synthesized, and these include N-carbobenzoxyglycyl- (10), hippuryl- (13), N-benzoyl-L-leucyl- (14), N-carbobenzoxyglycyl-L-leucyl- (18), N-carbobenzoxy-L-pyroglutamyl- (22), L-pyroglutamyl-L-leucyl- (19), and L-pyroglutamyl-L-phenylalanylcyanamide (20). All of these prodrugs of cyanamide raised ethanol-derived blood acetaldehyde levels in rats significantly over controls 3h after ip drug administration, and some of these were still capable of elevating blood acetaldehyde 16 h post drug administration. A selected group of cyanamide prodrugs were also evaluated by the oral route of administration and showed nearly equivalent activity as the ip route in elevating ethanol-derived blood acetaldehyde. These results suggest potential utility of these prodrugs as deterrent agents for the treatment of alcoholism.
