33993-24-7

Basic information

• Product Name: Cyclopropanecarboxylic acid anhydride
• Synonyms: Cyclopropanecarboxylic acid anhydride;NSC 167610;cyclopropanecarboxylic anhydride;Cyclopropanecarbonyl cyclopropanecarboxylate;CYCLOPROPYLCARBOXYLIC ACID ANHYDRIDE
• CAS NO: 33993-24-7
• Molecular Formula: C₈H₁₀O₃
• Molecular Weight: 154.1632
• Mol File: 33993-24-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 253.6°Cat760mmHg
• Flash Point: 113.7°C
• Appearance: /
• Density: 1.354g/cm³
• Vapor Pressure: 0.0181mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: Cyclopropanecarboxylic acid anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid anhydride(33993-24-7)
• EPA Substance Registry System: Cyclopropanecarboxylic acid anhydride(33993-24-7)

Safety Data

• Hazardous Substances Data: 33993-24-7(Hazardous Substances Data)

Usage

General Description

Cyclopropanecarboxylic acid anhydride, also known as methylenecyclopropane carboxylic anhydride, is a chemical compound with the molecular formula C5H6O3. It is an anhydride of cyclopropanecarboxylic acid, which is a carboxylic acid derived from cyclopropane. Cyclopropanecarboxylic acid anhydride is a highly reactive and unstable chemical used in organic chemistry as a building block for the synthesis of various compounds. It is utilized in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Due to its high reactivity, precautions must be taken when handling and using cyclopropanecarboxylic acid anhydride in laboratory settings.

InChI:InChI=1/C8H10O3/c9-7(5-1-2-5)11-8(10)6-3-4-6/h5-6H,1-4H2

Upstream product

• 117399-95-8 Cyclopropanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester 
• 4023-34-1 cyclopropanecarboxylic acid chloride 
• 1759-53-1 cyclopropanecarboxylic acid 

Downstream Products

• 93181-95-4 Cyclopropanecarboxylic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester 
• 187737-37-7 propene 
• 463-49-0 1,2-propanediene 
• 50888-73-8 butadiene monoxide 
• 1759-53-1 cyclopropanecarboxylic acid 
• 740872-83-7 cyclopropanecarboxylic acid (3-{4-[4(toluene-4-sulfonylamino)butyl]piperazin-1-yl}phenyl)amide 
• 54338-41-9 3',5'-dinitrocyclopropanecarboxanilide 
• 1422372-87-9 thiophenylmethyl-5-N-cyclopropylcarbonyl-4,7,8,9-tetra-OAc-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylate 

Relevant articles and documents

ADAMANTYLMETHYLAMINE DERIVATIVE AND USE THEREOF AS PHARMACEUTICAL

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Zinc(0)/dimethylformamide-mediated synthesis of symmetrical carboxylic anhydrides from acid chlorides

The high yielding synthesis of symmetrical carboxylic anhydrides from acid chlorides mediated by zinc dust in the presence of dimethylformamide is presented. A mechanism involving the reductive insertion of zinc(0) into the C-Cl bond of a Vilsmeier-type iminium intermediate as the crucial step is also proposed.

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The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cathepsin S.