339986-21-9Relevant academic research and scientific papers
On the synthesis of pyrinodemin A. Part 1: The location of the olefin
Romeril, Stuart P.,Lee, Victor,Baldwin, Jack E.,Claridge, Timothy D.W.
, p. 1127 - 1140 (2007/10/03)
The elucidation of the structure of the cytotoxic marine sponge alkaloid pyrinodemin A by synthesis is described. Based on the 13C NMR spectra of three double bond positional isomers and the natural product, it is concluded the C14′-C15′ isomer
20-Hydroxyeicosatetraenoic Acid (20-HETE): Structural Determinants for Renal Vasoconstriction
Yu, Ming,Alonso-Galicia, Magdalena,Sun, Cheng-Wen,Roman, Richard J.,Ono, Naoya,Hirano, Hitomi,Ishimoto, Tsuyoshi,Reddy, Y. Krishna,Katipally, Kishta Reddy,Reddy, Komandla Malla,Gopal, V. Raj,et al.
, p. 2802 - 2822 (2007/10/03)
The effects of natural and synthetic eicosanoids on the diameter of rat interlobular arteries studied in vitro were compared to that of the potent, endogenous vasoconstrictor 20-HETE. Vasoconstrictor activity was optimum for chain lengths of 20 - 22 carbo
Studies toward the total synthesis of the cytotoxic sponge alkaloid pyrinodemin A.
Baldwin,Romeril,Lee,Claridge
, p. 1145 - 1148 (2007/10/03)
[structure: see text]. The syntheses of the proposed structure of pyrinodemin A (1) and its cis double bond positional isomer (C15'-C16') in racemic form are described. The key reaction involved an intramolecular nitrone/double bond cycloaddition. Our res
