3400-55-3

Basic information

• Product Name: 2-BROMOPRIOPIONALDEHYDE DIETHYL ACETAL
• Synonyms: 2-BROMOPRIOPIONALDEHYDE DIETHYL ACETAL;2-bromo-1,1-diethoxypropane;2-Bromopriopionaldehyde diethyl acetyl;2-BroMopropionaldehyde Diethyl Acetal;Propane,2-broMo-1,1-diethoxy-
• CAS NO: 3400-55-3
• Molecular Formula: C₇H₁₅BrO₂
• Molecular Weight: 211.1
• EINECS: 222-270-0
• Mol File: 3400-55-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 209.453 °C at 760 mmHg
• Flash Point: 62℃
• Appearance: /
• Density: 1.198 g/mL at 25 °C
• Vapor Pressure: 0.293mmHg at 25°C
• Refractive Index: n20/D1.439
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-BROMOPRIOPIONALDEHYDE DIETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOPRIOPIONALDEHYDE DIETHYL ACETAL(3400-55-3)
• EPA Substance Registry System: 2-BROMOPRIOPIONALDEHYDE DIETHYL ACETAL(3400-55-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: TX4114500
• Hazardous Substances Data: 3400-55-3(Hazardous Substances Data)

Usage

Uses

2-Bromopropionaldehyde Diethyl Acetal is the 2-bromo derivative of Propionaldehyde diethyl acetal (P827700). 2-Bromopropionaldehyde Diethyl Acetal is also used as a reagent to synthesize piperazinylimidazo[1,2-a]pyrazines, compounds that have selective affinity for α-adrenergic receptor subtypes.

InChI:InChI=1/C7H15BrO2/c1-4-9-7(6(3)8)10-5-2/h6-7H,4-5H2,1-3H3

Upstream product

• 56-23-5 tetrachloromethane 
• 128-08-5 N-Bromosuccinimide 
• 4744-08-5 1,1-diethoxypropane 
• 123-38-6 propionaldehyde 
• 64-17-5 ethanol 
• 2396-42-1 2,4,6-Triethyl-[1,3,5]trioxane 
• 7726-95-6 bromine 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 79307-64-5 5-methyl-2-(3H)thiazolone 
• 7305-71-7 5-methyl-2-thiazol-2-amine 
• 3054-95-3 acrylaldehyde diethyl acetal 
• 55064-41-0 2-aminopropionaldehyde diethyl acetal 
• 3913-65-3 2-hydroxypropanal 
• 45667-45-6 2-methylimidazo<2,1-b>thiazole 
• 84066-11-5 3-methyl-6-chloro-8-bromoimidazo<1,2-a>pyrazine 
• 69994-64-5 2-benzenesulfenylpropionaldehyde diethylacetal 
• 4926-54-9 3-Methyl-5-bromoimidazo<1,2-a>pyridine 
• 1216222-91-1 6-bromo-3-methylimidazo[1,2-a]pyridine 
• 5221-69-2 5-methyl-2-phenylthiazole 
• 1542156-63-7 5-mehtylthiazol-2-yl-Ala-Phe-Gly 
• 19967-57-8 bromo-2 propanal 
• 108237-69-0 α-<2-Methyl-phenylmercapto>-propionaldehyd-diethylacetal 

Relevant articles and documents

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PREPARATION AND SYNTHETIC UTILIZATION OF 3-(ADENIN-9-YL)-2-HYDROXYALKANOIC ACIDS AND THEIR DERIVATIVES

Condensation of adenine and its substituted derivatives with 1,1-dialkoxy-2-bromoalkanes afforded substituted 2-(adenin-9-yl)-1,1-dialkoxyalkanes I and IV.Acid hydrolysis of I or IV, followed by reaction with alkali metal cyanides and acid hydrolysis, gave substituted 3-(adenin-9-yl)-2-hydroxyalkanoic acids II, V and VI.Methyl esters of these compounds (VIII) were converted into 3-(adenin-9-yl)alkane-1,2-diols IX by reduction with sodium borohydride. 3-(Adenin-9-yl)-2-methoxypropanoic acid (XVII) was obtained by oxidation of 9-(3-hydroxy-2-methoxypropyl)adenine (XVI)with sodium periodate; 4-(adenin-9-yl)-2-(S)-hydroxybutanoic acid (XXVII) was synthesized by oxidation of 9-(S)-(2-tetrahydropyranyloxy-4-hydroxybutyl)adenine (XXV), prepared from diethyl L-malate.Acid hydrolysis of XXV afforded 9-(S)-(2,4-dihydroxybutyl)adenine (XXVI). 4-(Adenin-9-yl)-3-hydroxypentanoic acid (XXIX) was obtained by reaction of malonic acid with 2-(adenin-9-yl)-1,1-diethoxypropane (IVa) in water.