340027-44-3Relevant academic research and scientific papers
The rhodium-catalyzed Pauson-Khand reaction
Kobayashi, Toshitake,Koga, Yuji,Narasaka, Koichi
, p. 73 - 87 (2001)
A rhodium carbonyl complex, [RhCl(CO)2]2, serves as a catalyst of the intra- and inter-molecular Pauson-Khand reaction. By the use of the rhodium catalyst, cyclopentenone derivatives are prepared from various 1,6- and 1,7-enynes unde
A preparation of haloalkylidene cyclopentanones
Cornwall, Nicholas J.,Linehan, Shaun,Weavers, Rex T.
, p. 2919 - 2922 (1997)
A radical-based 5-exo-dig cyclisation, initiated by addition of a trichloromethyl radical to an acyclic acetylenic ketone with an appropriately positioned double bond, has been employed to produce a variety of cyclic haloalkylidene cyclopentanones in mode
Scope of the intramolecular titanocene-catalyzed Pauson-Khand type reaction
Hicks, Frederick A.,Kablaoui, Natasha M.,Buchwald, Stephen L.
, p. 5881 - 5898 (2007/10/03)
A Pauson-Khand type conversion of enynes to bicyclic cyclopentenones employing the commercially available precatalyst titanocene dicarbonyl is described. This methodology shows excellent functional group tolerance for a group 4 metallocene-catalyzed process. The scope and limitations of this cyclization with respect to 1,6-, 1,7- and 1,8-enynes with a variety of terminal alkyne substituents, chiral enynes, and enynes containing substituted olefins are described in detail. A mechanism involving carbonylation of an intermediate titanacyclopentene has been proposed.
