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340127-55-1

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340127-55-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 340127-55-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,0,1,2 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 340127-55:
(8*3)+(7*4)+(6*0)+(5*1)+(4*2)+(3*7)+(2*5)+(1*5)=101
101 % 10 = 1
So 340127-55-1 is a valid CAS Registry Number.

340127-55-1Relevant articles and documents

Cell sugar transport channel inhibitor

-

, (2021/07/24)

The invention discloses a cell sugar transport channel inhibitor of which the structure is shown as a formula (I). The cell sugar transport channel inhibitor disclosed by the invention can target a cell sugar transport channel, and inhibit tumor cell prol

Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2

St. John, Sarah E.,Jensen, Katherine C.,Kang, Soosung,Chen, Yafang,Calamini, Barbara,Mesecar, Andrew D.,Lipton, Mark A.

, p. 6022 - 6037 (2013/09/23)

Resveratrol (3,5,4′-trihydroxylstilbene) has been proposed to elicit a variety of positive health effects including protection against cancer and cardiovascular disease. The highest affinity target of resveratrol identified so far is the oxidoreductase enzyme quinone reductase 2 (QR2), which is believed to function in metabolic reduction and detoxification processes; however, evidence exists linking QR2 to the metabolic activation of quinones, which can lead to cell toxicity. Therefore, inhibition of QR2 by resveratrol may protect cells against reactive intermediates and eventually cancer. With the aim of identifying novel inhibitors of QR2, we designed, synthesized, and tested two generations of resveratrol analogue libraries for inhibition of QR2. In addition, X-ray crystal structures of six of the resveratrol analogues in the active site of QR2 were determined. Several novel inhibitors of QR2 were successfully identified as well as a compound that inhibits QR2 with a novel binding orientation.

Toward globular macromolecules with functionalized interiors: Design and synthesis of dendrons with an interesting twist

Bharathi, Pandi,Zhao, Hongda,Thayumanavan

, p. 1961 - 1964 (2007/10/03)

(formula presented) Design and synthesis of a novel class of monodendrons, in which the functional units can potentially be directed toward the concave interiors of dendrimers, are described. The key feature of the design is the placement of the amphiphil

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