34016-27-8Relevant academic research and scientific papers
Regioselective functionalization of 2-(2′-fluorophenyl)-3-cyanopyridine and its cyclization to benzo[h]-1,6-naphthyridines
Cailly, Thomas,Begtrup, Mikael
experimental part, p. 1299 - 1307 (2010/04/04)
Benzo[h]-1,6-naphthyridines and 5-ones, selectively functionalized at C-2, C-3, C-5 and C-10, were obtained by alkyllithium-, lithium amide- or potassium hydroxide-induced anionic cyclization of 3-cyano-2-(2-fluorophenyl)pyridine, which was functionalized
ν-triazolines. Part 40. Thermal and photochemical transformations of 1-biaryl-5-amino-4,5-dihydro-ν-triazoles: A new synthetic approach to 6-alkylphenanthridines and aza-analogs
Erba, Emanuela,Pocar, Donato,Trimarco, Pasqualina
, p. 3535 - 3539 (2007/10/03)
1-Biaryl-5-morpholino-ν-triazolines 4 were prepared from aliphatic aldehydes 1, morpholine and 2-azidobiaryls 3. They underwent smooth thermal rearrangement to tertiary amidines 5 which were photochemically cyclized to 6-alkylphenanthridines 6a,b,e,f and analogs 6c,d and 8a,b with morpholine elimination. Direct photolysis of triazolines 4 afforded lower yields of the same compounds 6 together with by-products indicative of the mechanism of the photochemical rearrangement which is discussed.
