340160-98-7Relevant articles and documents
Synthetic analogues of beta-1,2 oligomannosides prevent intestinal colonization by the pathogenic yeast Candida albicans.
Dromer, Francoise,Chevalier, Reynald,Sendid, Boualem,Improvisi, Luce,Jouault, Thierry,Robert, Raymond,Mallet, Jean Maurice,Poulain, Daniel
, p. 3869 - 3876 (2007/10/03)
The pathogenic yeast Candida albicans displays at its cell surface beta-1,2 oligomannosides (beta-1,2-Mans). In contrast to the ubiquitous alpha-Mans, beta-1,2-Mans bind to galectin-3, a major endogenous lectin expressed on epithelial cells. The specific