340217-68-7Relevant academic research and scientific papers
Tandem cross-Rauhut-Currier/cyclization reactions of activated alkenes to give densely functionalized 3,4-dihydropyrans
Liu, Wen,Zhou, Jing,Zheng, Changwu,Chen, Xingkuan,Xiao, Hua,Yang, Yingquan,Guo, Yinlong,Zhao, Gang
, p. 1768 - 1773 (2011)
A novel tandem cross-Rauhut-Currier/cyclization reaction between α,β-unsaturated ketones was developed. Using DABCO (20 mol %) as the catalyst, a series of densely functionalized 3,4-dihydropyrans were obtained in excellent yields and stereoselectivities (up to 98% yield, >99:1 dr). A tentative catalytic cycle was proposed with key intermediates confirmed by ESIMS studies.
Organocatalytic Asymmetric [4+2] Cycloaddition of 1-Acetylcyclopentene and 1-Acetylcyclohexene for the Synthesis of Fused Carbocycles
Nath, Utpal,Pan, Subhas Chandra
supporting information, p. 6457 - 6461 (2017/12/01)
The first organocatalytic asymmetric [4+2]-cycloaddition reaction of 1-acetylcyclopentenes and 1-acetylcyclohexenes was developed. Enones having cyano groups were used as the dienophiles in this method. The reaction provides a useful practical route to th
