340258-57-3Relevant academic research and scientific papers
Direct transformation of arylpropynes to acrylamides via a three-step tandem reaction
Qiu, Jun,Zhang, Ronghua
supporting information, p. 1556 - 1560 (2014/03/21)
A novel and metal-free acrylamides formation between arylpropynes and hydroxylamine hydrochloride through sp3 C-H and C-C bond cleavage has been achieved with DDQ as an oxidant. The mechanistic study shows that the acrylamides are formed through a three-step tandem sequence, including cross-dehydrogenative-coupling (CDC) reaction, aza-Meyer-Schuster rearrangement and Beckmann rearrangement. This journal is The Royal Society of Chemistry 2014.
Iron-catalyzed C-H and C-C bond cleavage: A direct approach to amides from simple hydrocarbons
Qin, Chong,Zhou, Wang,Chen, Feng,Ou, Yang,Jiao, Ning
supporting information; experimental part, p. 12595 - 12599 (2012/01/15)
Something functional: The title reaction proceeds in the presence of azide and water to deliver amides in high yields, and it can be used in a ring-expansion strategy to generate lactams. A mechanism is proposed based on experimental results. This reaction offers a new approach to functionalizing simple and readily available hydrocarbons. DDQ=2,3-dichloro-5,6-dicyano-1,4- benzoquinone. Copyright
