34034-29-2Relevant articles and documents
An improved synthesis of β-carboline and azepino-and azocino[3,4-b]indole derivatives from lactams
Tokmakov
, p. 211 - 216 (2014/06/23)
The Vilsmeier formylation of butyrolactam, N-methylbutyrolactam, N-methylvalerolactam, and N-methylcaprolactam followed by treatment with aryl hydrazines afforded the 2,3,4,9-tetrahydro-1H-β-carbolin-1-ones, 3,4,5,10-tetrahydroazepino[3,4-b]indol-1(2H)-ones, and 2,3,4,5,6,11-hexahydro- 1H-azocino[3,4-b]indol-1-ones. The synthesis was performed as a one-pot process without isolating the intermediate a-formyl lactams.
REACTION OF ARYLHYDRAZINES WITH α-FORMYLBUTYROLACTAM DERIVATIVES
Tokmakov, G. P.,Zemyanova. T. G.,Grandberg, I. I.
, p. 47 - 51 (2007/10/02)
The Vilsmeier formylation of butyrolactam and N-phenylbutyrolactam has given their α-dimethylaminomethylene derivatives.The reaction of the latter with α-substituted arylhydrazines leads to the formation of 1-oxo-1,2,3,4-tetrahydro-β-carbolines.When unsub