34039-34-4Relevant academic research and scientific papers
Study on the ArI-catalyzed intramolecularoxy-cyclization of 2-alkenylbenzamides to benzoiminolactones
Deng, Xiaojun,He, Wei,Huang, Xie,Ji, Nan,Liu, Huixia
supporting information, p. 3654 - 3658 (2020/06/03)
A new intramolecularoxy-cyclization of 2-alkenylbenzamides catalyzed by ArI has been developed. This protocol is highlighted by its metal-free catalytic system and extremely short reaction time, providing efficient and straightforward access to various benzoiminolactones in good to excellent yields. Interestingly, a regioselective transformation occurred when using two different reaction systems. Mechanistic studies suggested thatmCPBA acts as both oxidant and ligand at the IIIIcenter, and the Lewis acid BF3accelerated ligand exchange and reductive elimination in the catalytic process.
Synthesis of Isoindolinones through Intramolecular Amidation of ortho-Vinyl Benzamides
Wei, Wen-tao,Chen, Zhen-yu,Lin, Yong-lu,Chen, Ri-xing,Wang, Qi,Wu, Qing-guang,Liu, Si-jun,Yan, Ming,Zhang, Xue-jing
, p. 1972 - 1976 (2020/04/20)
A synthetic approach of isoindolinones through intramolecular amidation of ortho-vinyl benzamides was reported. A variety of N-aryl isoindolinone derivatives were prepared in moderate to excellent yields using perfluorobutyl iodide as oxidant. (Figure pre
Intramolecular Hydroamidation of ortho-Vinyl Benzamides Promoted by Potassium tert-Butoxide/N,N-Dimethylformamide
Chen, Zhen-Yu,Wu, Liang-Yu,Fang, Hai-Sheng,Zhang, Ting,Mao, Zhi-Feng,Zou, Yong,Zhang, Xue-Jing,Yan, Ming
, p. 3894 - 3899 (2017/10/07)
An intramolecular hydroamidation of ortho-vinyl benzamides had been developed. The reaction was promoted efficiently by potassium tert-butoxide and N,N-dimethylformamide without the need for strong oxidants or transition-metal catalysts. A series of dihyd
A new and practical PIFA-promoted olefin amidohydroxylation: Six- versus five-membered ring formation
Serna, Sonia,Tellitu, Imanol,Domínguez, Esther,Moreno, Isabel,SanMartín, Raúl
, p. 3483 - 3486 (2007/10/03)
A novel access to the isoindolinone and isoquinolin-2-one skeletons from adequately substituted aromatic precursors is described. The key intramolecular cyclization step was performed by the action of phenyliodine(III)bis(trifluoroacetate) (PIFA) on the c
