3404-61-3Relevant articles and documents
Light-driven biocatalytic reduction of α,β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers
Peers, Martyn K.,Toogood, Helen S.,Heyes, Derren J.,Mansell, David,Coe, Benjamin J.,Scrutton, Nigel S.
, p. 169 - 177 (2015/12/31)
Efficient and cost effective nicotinamide cofactor regeneration is essential for industrial-scale bio-hydrogenations employing flavin-containing biocatalysts such as the Old Yellow Enzymes. A direct flavin regeneration system using visible light to initiate a photoredox cycle and drive biocatalysis is described, and shown to be effective in driving biocatalytic activated alkene reduction. Using Ru(ii) or Ir(iii) complexes as photosensitizers, coupled with an electron transfer mediator (methyl viologen) and sacrificial electron donor (triethanolamine) drives catalytic turnover of two Old Yellow Enzymes with multiple oxidative substrates. Therefore, there is great potential in the development of light-driven biocatalytic systems, providing an alternative to the reliance on enzyme-based cofactor regeneration systems.
METAL-HALOGEN INTERCHANGE BETWEEN t-BUTYLLITHIUM AND 1-IODO-5-HEXENES PROVIDES NO EVIDENCE FOR SINGLE-ELECTRON TRANSFER
Bailey, William F.,Patricia, Jeffrey J.,Nurmi, Timo T.,Wang, Wei
, p. 1861 - 1864 (2007/10/02)
No products attributable to cyclization of 5-hexen-1-yl radicals have been detected in reactions of t-butyllithium with 1-iodo-5-hexenes at -78 gradC.Such experiments provide no evidence for the intermediacy of free-radicals in the metal-halogen interchange of primary alkyliodides with t-C4H9Li.
CYCLIZATION OF C7-ALKANES OVER Pt BLACK CATALYST
Zimmer, H.,Paal, Z.,Tetenyi, P.
, p. 513 - 532 (2007/10/02)
C6-and C5-cyclization of heptane isomers (and also, olefin formation as a related process) over Pt-black have been studied in pulse and circulation systems.Hydrogendeficient conditions favour aromatization, via presumably terminal olefins.C5-Cyclization in the presence of more hydrogen is accompanied by internal olefin formation.Relative reactivities of all heptane isomers have been measured; this shows that cyclization is easier between terminal methyl groups.Optimum hydrogen pressures for both types of cyclization have been determined (and compared with hydrogenolysis, too).Earlier mechanism suggestion for aromatization and cyclopentane formation have been confirmed; the distinction between two types of bond shift mechanisms producing aromatics (from substituted pentanes) and saturated isomers, respectively, has recieved additional support facilitating the identification of these two reactions with mechanisms proposed in the literature.
