34041-41-3Relevant articles and documents
A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β
Zhao, Li-Ming,Jin, Hai-Shan,Liu, Jinzhong,Skaar, Todd C.,Ipe, Joseph,Lv, Wei,Flockhart, David A.,Cushman, Mark
, p. 5400 - 5409 (2016)
The design and synthesis of dual aromatase inhibitors/selective estrogen receptor modulators (AI/SERMs) is an attractive strategy for the discovery of new breast cancer therapeutic agents. Previous efforts led to the preparation of norendoxifen (4) deriva
TRIPHENYLETHYLENE COMPOUNDS AND USES THEREOF
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Paragraph 0147-0148; 0149, (2017/06/19)
Triphenylethylene compounds as dual aromatase inhibitors and selective estrogen receptors modulators are described. Also described are methods for treating patients of breast cancers, and patients of breast cancer comorbid with osteoporosis, using the des