34052-66-9

Basic information

• Product Name: 1,2-di(prop-1-yn-1-yl)benzene
• Synonyms: 1,2-di(prop-1-yn-1-yl)benzene
• CAS NO: 34052-66-9
• Molecular Weight: 154.211
• Mol File: 34052-66-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,2-di(prop-1-yn-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-di(prop-1-yn-1-yl)benzene(34052-66-9)
• EPA Substance Registry System: 1,2-di(prop-1-yn-1-yl)benzene(34052-66-9)

Safety Data

• Hazardous Substances Data: 34052-66-9(Hazardous Substances Data)

Upstream product

• 74-99-7 prop-1-yne 
• 583-53-9 2,3-dibromobenzene 
• 860556-20-3 1,2-bis-(1-bromo-propyl)-benzene 
• 33996-35-9 1,2-dipropenyl-benzene 
• 851758-56-0 (E,E)-bis-1,2-(2,2-dibromoethenyl)benzene 
• 74-88-4 methyl iodide 
• 615-42-9 1,2-Diiodobenzene 
• 75-89-8 2,2,2-trifluoroethanol 
• 93769-24-5 1-<2-(1-Propin-1-yl)phenyl>-2-propanon 
• 93769-03-0 (Z)-1-methyl-2-<2-(1-propyn-1-yl)phenyl>vinyl triflate 
• 64-17-5 ethanol 
• 33996-36-0 1,2-bis-(1,2-dibromo-propyl)-benzene 

Downstream Products

• 33996-37-1 1,2-Dimethyl-4-3-<2-propin-(1)-yl-phenyl>-azulen 
• 33996-38-2 1,2-Dimethyl-8--3-<2-propin-(1)-yl-phenyl>-azulen 

Relevant articles and documents

Synthesis of Fulvene Vinyl Ethers by Gold Catalysis

Gold-catalyzed cyclization of 1,5-diynes with ketones as reagents and solvent provides diversely substituted vinyl ethers under mild conditions. The regioselectivity of such gold-catalyzed cyclizations is usually controlled by the scaffold of the diyne. H

Synthesis of arenediynes via the vinylidenecarbene-acetylene rearrangement

A convenient method for the two-step synthesis of arenediynes from 1,2-arenedialdehydes is reported. Dibromomethylenation of dialdehydes under Corey-Fuchs conditions (CBr4, Ph3P, Zn) provides the tetrabromides in excellent yields. Treatment of the tetrabromides with n-BuLi or LDA affords 3,4-unsaturated 1,5-diynes, the key structural moiety present in several naturally occurring antitumour antibiotics, in varying yields. The key intermediates in these transformations appear to be vinylidenecarbenes or carbenoids, generated in situ via metal-halogen exchange and elimination.

Synthesis and Solvolysis of (Z)/(E)-1-Methyl-2-vinyl Triflate and 1-Methylene-2-ethyl Triflate

The synthesis and solvolysis of the triflates (Z)/(E)-8 and 20 in various solvents are described.The (E)-triflate 8 reacts in trifluoroethanol by rearrangement via the intermediate naphthyl cation 9 to give the naphthyl ether 22 and the naphthyl triflate