34058-50-9

Basic information

• Product Name: 2-Methyl-1H-indole-4-carboxylic acid
• Synonyms: 2-Methyl-1H-indole-4-carboxylic acid;2-Methyl-1H-indole-4-Carbocylic acid
• CAS NO: 34058-50-9
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175
• EINECS: -0
• Mol File: 34058-50-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 228-231℃
• Boiling Point: 417.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.340
• Storage Temp.: 2-8°C
• PKA: 3.99±0.30(Predicted)
• CAS DataBase Reference: 2-Methyl-1H-indole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-1H-indole-4-carboxylic acid(34058-50-9)
• EPA Substance Registry System: 2-Methyl-1H-indole-4-carboxylic acid(34058-50-9)

Safety Data

• Hazardous Substances Data: 34058-50-9(Hazardous Substances Data)

Usage

General Description

2-Methyl-1H-indole-4-carboxylic acid is a chemical compound with the molecular formula C10H9NO2. It is a derivative of indole, a heterocyclic aromatic compound commonly found in nature. This particular compound contains a carboxylic acid functional group and a methyl group at the 2-position of the indole ring. It has the potential for use in pharmaceutical and medicinal applications due to its structural resemblance to other biologically active molecules. Furthermore, it may also have potential uses in organic synthesis as a building block for designing new compounds with desired properties.

Upstream product

• 6127-18-0 4-bromo-2-methyl-1H-indole 
• 359585-96-9 2-methyl-1H-indol-4-yl trifluoromethanesulfonate 
• 35320-67-3 4-hydroxy-2-methyl-1H-indole 
• 34058-51-0 methyl 2-methyl-1H-indole-4-carboxylate 

Downstream Products

• 34058-51-0 methyl 2-methyl-1H-indole-4-carboxylate 
• 756478-92-9 benzyl [1-(4-butoxybenzoyl)-2-methyl-1H-indol-4-yl]acetate 
• 359586-03-1 benzyl 1-(4-butoxybenzoyl)-2-methyl-1H-indole-4-carboxylate 
• 359583-47-4 1-(4-butoxybenzoyl)-2-methyl-1H-indole-4-carboxylic acid 
• 208773-39-1 benzyl 2-methyl-1H-indole-4-carboxylate 

Relevant articles and documents

AMINOACYLINDAZOLE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES

2-Acylindazole compounds of formula I or formula II are disclosed. These compounds inhibit Coagulation Factor XIIa. They are useful to treat autoimmune diseases.

Development of prostaglandin D2 receptor antagonist: discovery of highly potent antagonists.

The process of discovery for highly potent prostaglandin D(2) (PGD(2)) receptor antagonists is reported. A series of N-(p-alkoxy)benzoyl-2-methylindole-4-acetic acids were synthesized and identified as a new class of selective PGD(2) receptor antagonists.

INDOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT

Indole derivatives represented by formula (I) ???wherein all symbols represent the same as that in specification), production methods thereof, and DP receptor antagonist comprising them as active ingredients. Since the compounds of formula (I) binds and antagonizes to DP receptor, they are useful for the prevention and/or treatment against allergic diseases, diseases accompanied with itching, secondary diseases generated by behaviors caused by itching, inflammation, chronic obstructive pulmonary disease, ischemic reperfusion disorder, cerebrovascular disorder, pleuritis complicated by rheumatoid arthritis, ulcerative colitis.