34069-64-2

Upstream product

• 118908-29-5 6-[(1R,2R,3S,5S)-3,5-Diacetoxy-2-((E)-4-methoxycarbonyl-but-2-enyl)-cyclopentyl]-4-oxo-hexanoic acid methyl ester 
• 31752-99-5 (-)-Corey lactone 5-(4-phenylbenzoate) 
• 118908-21-7 3-(2-{2-[(3aR,4R,5R,6aS)-2-Hydroxy-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-4-yl]-ethyl}-[1,3]dithiolan-2-yl)-propionic acid methyl ester 
• 118908-20-6 methyl 3-<2-<2-(3-oxo-c-7-tetrahydropyranyloxy-cis-bicyclo<3.3.0>octan-t-6-yl)ethyl>-1,3-dithiolan-2-yl>propionate 
• 118908-17-1 Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-(5-methoxycarbonyl-3-oxo-pentyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 
• 118908-16-0 Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-((E)-5-methoxycarbonyl-3-oxo-pent-1-enyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 
• 118908-18-2 methyl 3-<2-(2-octan-t-6-yl>ethyl)-1,3-dithiolan-2-yl>propionate 
• 38754-71-1 (3aR,4R,5R,6aS)-4-formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl biphenyl-4-carboxylate 
• 118908-22-8 3-(2-{2-[(1R,2R,3S,5R)-3-Hydroxy-2-[(E)-4-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-but-2-enyl]-5-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-ethyl}-[1,3]dithiolan-2-yl)-propionic acid methyl ester 
• 118908-25-1 (E)-5-[(1R,2R,3R,5S)-5-Acetoxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-pent-3-enoic acid methyl ester 
• 118934-04-6 (E)-5-((1R,2R,3R,5S)-5-Acetoxy-3-methanesulfonyloxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-cyclopentyl)-pent-3-enoic acid methyl ester 
• 118908-27-3 (E)-5-((1R,2R,3S,5S)-3,5-Diacetoxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-cyclopentyl)-pent-3-enoic acid methyl ester 
• 118908-24-0 (E)-5-[(1R,2R,3R,5S)-5-Hydroxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-pent-3-enoic acid methyl ester 
• 118908-23-9 (E)-5-[(1R,2R,3R,5S)-2-{2-[2-(2-Carboxy-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-pent-3-enoic acid 

Relevant academic research and scientific papers

SYNTHESIS OF THE MAJOR URINARY METABOLITE OF PROSTAGLANDIN D2

Starting from the Corey lactone (3), the total synhesis of a specific urinary metabolite of prostaglandin D2, viz., (Z)-9α,11β-dihydroxy-15-oxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid (1) and its 5E-isomer is described.The synthetic mater