340697-25-8Relevant academic research and scientific papers
Thyroid receptor ligands. Part 7: Indirect antagonists of the thyroid hormone receptor with improved affinity
Malm, Johan,Gordon, Sandra,Brandt, Peter,Carlsson, Bo,Agback, Peter,Baeckbro Saeidi, Anna,Sandberg, Johnny
, p. 2018 - 2021 (2007)
Based on the concept of 'indirect antagonism' of nuclear receptors, a series of thyroid hormone receptor (TR) antagonists were prepared with improved affinity compared with what was previously described. The results of a binding assay for the human TR and
NOVEL PHARMACEUTICAL COMPOSITIONS
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Page/Page column 39, (2010/02/14)
The invention provides compounds of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt, for use in the treatment or prophylaxis of condition mediated by an androgen receptor.
Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
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Page/Page column 17, (2010/02/14)
This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac arrhythmias, thyrotoxicosis and subclinical hyperthyrodism.
