340698-00-2

Upstream product

• 219692-16-7 methyl 3-(3,5-dibromo-4-hydroxyphenyl)propanoate 
• 3958-57-4 1-bromomethyl-3-nitrobenzene 
• 340697-25-8 3-[3,5-dibromo-4-(3-nitrobenzyloxy)phenyl]propionic acid 

Relevant academic research and scientific papers

Thyroid receptor ligands. Part 7: Indirect antagonists of the thyroid hormone receptor with improved affinity

Based on the concept of 'indirect antagonism' of nuclear receptors, a series of thyroid hormone receptor (TR) antagonists were prepared with improved affinity compared with what was previously described. The results of a binding assay for the human TR and

Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders

This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac arrhythmias, thyrotoxicosis and subclinical hyperthyrodism.