34073-34-2Relevant academic research and scientific papers
Palladium-catalyzed decarboxylative a polyfluoroarylation of ketones
Doi, Ryohei,Hayashi, Kanako,Sato, Yoshihiro
, p. 1181 - 1183 (2021/06/06)
Herein, we report palladium-catalyzed decarboxylative a-polyfluoroarylation of ketones. As a result of reaction condition screening, XPhos and Ruphos were selected as ancillary ligands for Pd(0) catalysts. The reaction was applied to a variety of substrates. A cross-over experiment was conducted to gain insight into the reaction mechanism.
Synthesis of polyfluorinated benzofurans
Politanskaya, Larisa,Troshkova, Nadezhda,Tretyakov, Evgeny,Xi, Chanjuan
, (2019/09/18)
A simple and efficient approach to the synthesis of fluorinated benzofurans including the Sonogashira cross-coupling of o-iodophenols with terminal Ph- and n-Bu-acetylenes, followed by intramolecular cyclization, in good to excellent yields is reported.
Photocatalytic hydrodefluorination: Facile access to partially fluorinated aromatics
Senaweera, Sameera M.,Singh, Anuradha,Weaver, Jimmie D.
supporting information, p. 3002 - 3005 (2014/03/21)
Polyfluorinated aromatics are essential to materials science as well as the pharmaceutical and agrochemical industries and yet are often difficult to access. This Communication describes a photocatalytic hydrodefluorination approach which begins with easily accessible perfluoroarenes and selectively reduces the C-F bonds. The method allows facile access to a number of partially fluorinated arenes and takes place with unprecedented catalytic activity using a safe and inexpensive amine as the reductant.
