340825-20-9 Usage
Uses
Used in Pharmaceutical Industry:
Ethyl 2-(3-chloro-4-fluorophenyl)acetate is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new drugs with specific therapeutic properties, contributing to advancements in medicine.
Used in Agrochemical Industry:
In the agrochemical sector, ethyl 2-(3-chloro-4-fluorophenyl)acetate serves as an essential intermediate for the production of agrochemicals. Its incorporation in the synthesis process aids in the development of effective pesticides and other agricultural chemicals that enhance crop protection and yield.
Used in Perfumery:
Ethyl 2-(3-chloro-4-fluorophenyl)acetate is employed as a fragrance ingredient in the perfumery industry. Its fruity odor adds a pleasant and distinctive scent to various perfumes and fragrance products, enhancing their appeal to consumers.
Used in Flavor Industry:
In the flavor industry, ethyl 2-(3-chloro-4-fluorophenyl)acetate is used as a flavoring agent. Its fruity aroma contributes to the enhancement of flavors in food and beverage products, providing a unique taste experience for consumers.
Check Digit Verification of cas no
The CAS Registry Mumber 340825-20-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,0,8,2 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 340825-20:
(8*3)+(7*4)+(6*0)+(5*8)+(4*2)+(3*5)+(2*2)+(1*0)=119
119 % 10 = 9
So 340825-20-9 is a valid CAS Registry Number.
340825-20-9Relevant academic research and scientific papers
2-(Halogenated Phenyl) acetamides and propanamides as potent TRPV1 antagonists
Ann, Jihyae,Bahrenberg, Gregor,Blumberg, Peter M.,Choi, Sun,Christoph, Thomas,Do, Nayeon,Frank-Foltyn, Robert,Ha, Heejin,Jeong, Jin Ju,Kang, Jin Mi,Kim, Changhoon,Kwon, Sun Ok,Lee, Jeewoo,Lee, Sunho,Lesch, Bernhard,Stockhausen, Hannelore,Vu, Thi Ngoc Lan,Yoon, Sanghee
, (2021/07/28)
A series consisting of 117 2-(halogenated phenyl) acetamide and propanamide analogs were investigated as TRPV1 antagonists. The structure–activity analysis targeting their three pharmacophoric regions indicated that halogenated phenyl A-region analogs exhibited a broad functional profile ranging from agonism to antagonism. Among the compounds, antagonists 28 and 92 exhibited potent antagonism toward capsaicin for hTRPV1 with Ki[CAP] = 2.6 and 6.9 nM, respectively. Further, antagonist 92 displayed promising analgesic activity in vivo in both phases of the formalin mouse pain model. A molecular modeling study of 92 indicated that the two fluoro groups in the A-region made hydrophobic interactions with the receptor.
