341-24-2

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
7-Fluoro indazole is used as a key building block for the development of new pharmaceuticals and agrochemicals, due to its unique chemical structure and potential biological activity.
Used in Medicinal Chemistry and Drug Discovery:
As a research tool, 7-Fluoro indazole aids in the identification and optimization of lead compounds, contributing to the advancement of novel therapeutic agents.
Used in Treatment of Various Diseases and Conditions:
7-Fluoro indazole is being studied for its potential applications in the treatment of a range of diseases and conditions, owing to its demonstrated biological activity.
Used in Coordination Chemistry:
7-Fluoro indazole has been investigated for its potential as a ligand, which could enhance the properties of metal complexes and contribute to the development of new materials with specific applications.
Used in Material Design:
7-FLUORO INDAZOLE is also considered as a component in the design of new materials, leveraging its chemical properties to create innovative substances with unique characteristics for various industries.

InChI:InChI=1/C7H5FN2/c8-6-3-1-2-5-4-9-10-7(5)6/h1-4H,(H,9,10)

Upstream product

• 2646-91-5 2,3-difluorobenzaldehyde 
• 18355-80-1 2,3-difluoroacetophenone 
• 394-50-3 3-fluorosalicylaldehyde 

Downstream Products

• 1105175-05-0 7-fluoro-5-nitro-1H-indazole 
• 1010103-16-8 7-fluoro-4-nitro-1H-indazole 

Relevant academic research and scientific papers

Synthesis, antifungal activity and qsar of novel pyrazole amides as succinate dehydrogenase inhibitors

We design and synthesize a series of novel pyrazole amides based on the commercialized fungicides and our previous work. The antifungal activity was tested in vitro by mycelial growth inhibition assay. The results show that all the compounds are of antifungal activities against the tested fungi at different levels. Among them, N-(2-(7-bromo-5-chloro-1H-indazol-1-yl)phenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide (Vk) exhibited higher antifungal activity than boscalid against two fungi. Molecular docking study revealed that the carbonyl oxygen atom of Vk forms two hydrogen bonds toward the hydroxyl hydrogens of TYR58 and TRP173.

HETEROCYCLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY

The present invention is related to a compound represented by formula (I), wherein X1, X2, X3, X4, X5, R5, R6, R7, R8, n, p, q, ring A and ring B are as described in the specification, or a

Fluorinated analogues of marsanidine, a highly α2-AR/imidazoline I1 binding site-selective hypotensive agent. Synthesis and biological activities

The aim of these studies was to establish the influence of fluorination of the indazole ring on the pharmacological properties of two selective α2-adrenoceptor (α2-AR) agonists: 1-[(imidazolidin-2-yl)imino]-1H-indazole (marsanidine,

THIENOPYRIDINE DERIVATIVE, OR QUINOLINE DERIVATIVE, OR QUINAZOLINE DERIVATIVE, HAVING C-MET AUTOPHOSPHORYLATION INHIBITING POTENCY

An objective of the present invention is to provide compounds having antitumor activity. According to the present invention, there is provided compounds represented by formula (I) and pharmaceutically acceptable salts thereof, and solvates thereof: wherei