34103-08-7Relevant academic research and scientific papers
Mild, Efficient, One-Pot Synthesis of Imidazolones Promoted by N,O-Bistrimethylsilylacetamide (BSA)
Muselli, Micka?l,Colombeau, Ludovic,Hédouin, Jonathan,Hoarau, Christophe,Bischoff, Laurent
, p. 2819 - 2825 (2016)
The formation of imidazolones by means of dehydrative cyclization was developed, using bistrimethylsilylacetamide. This highly versatile, friendly, safe, and cost-effective reagent exhibited a very large scope of starting materials, since it can promote the formation of 4-benzylidene imidazolones, 4,4-dialkyl-imidazolones, bearing alkyl, aryl, or even no substituent at C2, the latter being unavailable by classical methods. This reagent also afforded clean and high-yielding one-pot reactions in the presence of amine or imine reagents.
