34104-05-7Relevant academic research and scientific papers
Cobalt-Catalyzed (E)-β-Selective Hydrogermylation of Terminal Alkynes
Radzhabov, Maxim R.,Mankad, Neal P.
supporting information, p. 3221 - 3226 (2021/05/04)
A cobalt-catalyzed method for the hydrogermylation of alkynes is reported, providing a selective and accessible route to (E)-β-vinyl(trialkyl)germanes from terminal alkynes and HGeBu3. As shown in multiple examples, the developed method demonstrates a broad functional group tolerance an practical utility for late-stage hydrogermylation of natural products. The method is compatible with alkynes bearing both aryl and alkyl substituents, providing unrivaled selectivity for previously challenging 1° alkyl-substituted alkynes. Moreover, the catalyst used in this method, Co2(CO)8, is a cheap and commercially available reagent. Conducted mechanistic studies supported the syn-addition of Bu3GeH to an alkyne π-complex.
Application of Free Radical Substitution Reaction into Interconversion of 1-Alkenylsulfides, 1-Alkenylgermanes, and 1-Alkenylstannanes
Ichinose, Yoshifumi,Oshima, Koichiro,Utimoto, Kiitiro
, p. 669 - 672 (2007/10/02)
Treatment of 1-alkenylsulfides or 1-alkenylstannanes with Ph3GeH in the presence of Et3B provides 1-alkenyltriphenylgermanes in good yields. 1-Alkenylstannanes are converted into 1-alkenylsulfides easily with PhSH-Et3B, whereas 1-alkenyltriphenylgermanes are recovered unchanged upon treatment with Ph3SnH-Et3B or PhSH-Et3B.
Palladium Catalyzed Hydrostannylation and Hydrogermylation of Acetylenes
Ichinose, Yoshifumi,Oda, Hiroji,Oshima, Koichiro,Utimoto, Kiitiro
, p. 3468 - 3470 (2007/10/02)
Treatment of acetylenes with Ph3SnH or Ph3GeH in the presence of a catalytic amount of Pd(PPh3)4 provides the corresponding alkenyltriphenylstannanes or alkenyltriphenylgermanes in good yields.
