3411-03-8Relevant articles and documents
Method for producing halogen-substituted aromatic aldehyde
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Page/Page column 6, (2008/06/13)
In the production method of the invention, a halogen-substituted aromatic compound is reacted with carbon monoxide in the presence of hydrogen fluoride and boron trifluoride into a corresponding halogen-substituted aromatic aldehyde. By the use of hydrogen fluoride and boron trifluoride, the para position to halogen atom is selectively formylated to provide the halogen-substituted aromatic aldehyde in high yields in a short reaction time even at temperatures lower than room temperature.
IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF
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, (2008/06/13)
Imidazole compounds represented by general formula (I): wherein each symbol is as defined in the specification, and salts thereof, and a pharmaceutical composition containing same are provided. These compounds are useful in treating the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle cell inhibitory action and an allergy inhibitory action.
THE OXIDATION OF ALDEHYDES TO ACIDS WITH CALCIUM HYPOCHLORITE
Nwaukwa, Stephen O.,Keehn, Philip M.
, p. 3131 - 3134 (2007/10/02)
Calcium hypochlorite is an efficient reagent for the oxidation of aldehydes to the corresponding acids.Reactions are carried out at ambient temperature in aqueous acetonitrile-acetic acid solution.Aliphatic aldehydes and aromatic aldehydes with electron withdrawing groups afford good to excellent yields.Nuclear chlorination is the preferred reaction in aromatic aldehydes with electron donating groups.