3411-56-1Relevant articles and documents
Biological activities and correlations tendency of electrochemical properties of some indolizino [1,2-b] quinoline derivatives
Canete, A.,Armijo, F.,Del Valle, M. A.,Tapia, R. A.,Pessoa, C. D.,Cantuarias, L.,Recabarren, G.,Theoduloz, C.
, p. 1126 - 1129,4 (2020/08/24)
We report the preparation of a series of indolylquinone and pyridine derivatives in order to evaluate structure-activity relationships in human gastric (AGS), lung (SK-MES-1), bladder (J82) cancer cell lines and human normal lung fibroblasts (MCR-5). Two correlations tendency between half-wave redox potentials against their antineoplasic activity were found making it possible to establish that for epithelial human gastric cancer (AGS) cell lines and human normal lung fibroblasts (MCR-5). The quinone bioreduction should correspond to a one electron process under normomix conditions, whilst for all other lines this process should correspond to a two electron attachment via a hypoxic process.
Reaction of 2,3-dichloro-1,4-naphthoquinone with some active methylene compounds in different basic media
Hammam,Fandy,Hassan
, p. 400 - 405 (2007/10/03)
Reaction of 2,3-dichloro-1,4-naphthoquinone with some active methylene compounds, such as malononitrile and cyanoacetamide, under various basic conditions has been investigated. A mechanism for these reactions is proposed.
Heterocyclic Quinonoid Chromophoric Systems: Part VII- Reaction of 2,3-Dichloro-1,4-naphthoquinone with Nitromethane and Vinylogously Substituted Nitromethanes, Di- and Trinitrotoluenes
Ayyangar, N. R.,Lugade, A. G.,Rajadhyaksha, M. N.
, p. 1126 - 1132 (2007/10/02)
Interaction of 2,3-Dichloro-1,4-naphthoquinone (1) with nitromethane and nitrotoluenes (DNT and TNT) containing a reactive methylene group in the presence of heterocyclic bases affords the nitro- and nitroaryl-naphthindolizinediones (4a-j, 5a-d, and 6a,b)
