34128-24-0

Upstream product

• 29682-12-0 1-[4-(benzyloxy)-2-hydroxyphenyl]ethanone 
• 141-78-6 ethyl acetate 

Downstream Products

• 34086-77-6 7-benzyloxy-2-methyl-4H-1-benzopyran-4-one 
• 6320-42-9 7-hydroxy-2-methyl-4H-chromen-4-one 

Relevant academic research and scientific papers

A Convenient Synthesis of Linear 2-Methylpyranochromones

A convenient synthesis of linear 2-methylpyranochromones, viz., spatheliachromen(5-hydroxy-2,2,8-trimethyl-2H,6H-benzodipyran-6-one), O-methylspatheliachromen (5-methoxy-2,2,8-trimethyl-2H,6H-benzodipyran-6-one) (8) and O-methylallopteroxylin (5-methoxy-2,8,8-trimethyl-4H,8H-benzodipyran-4-one> is described by blocking the eighth position of the corresponding 7-propargyl ether derivative 7-(1,1-dimethyl-2-propynyloxy)-8-iodo-5-methoxy-2-methyl-4H-1-benzopyran-4-one with iodine followed by thermal cyclization.The linear pyranochromones 2,2,8-trimethyl-2H,6H-benzodipyran-6-one and 8 are also synthesized starting with the easily available appropriate 3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-7-ols following the steps of Claisen condensation with ethyl acetate, cyclization with ethanolic sulfuric acid followed by dehydrogenation with NBS.