34145-05-6

Basic information

• Product Name: 2,5-DICHLOROBENZYL ALCOHOL
• Synonyms: 2,5-DICHLOROBENZYL ALCOHOL;RARECHEM AL BD 0427;Benzenemethanol, 2,5-dichloro-;2,5-dichlorobenzylic alcohol;(2,5-Dichloro-phenyl)-methanol;2,5-Dichlorobenzylalcohol,99%;2,5-DICHLOROBENZYL ALCOHOL 99%;2,5-Dichlorobenzenemethanol
• CAS NO: 34145-05-6
• Molecular Formula: C₇H₆Cl₂O
• Molecular Weight: 177.03
• EINECS: 251-850-6
• Product Categories: Benzhydrols, Benzyl & Special Alcohols;Alcohols;C7 to C8;Oxygen Compounds
• Mol File: 34145-05-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 79-80 °C(lit.)
• Boiling Point: 266℃
• Flash Point: 114℃
• Appearance: white fine crystalline powder
• Density: 1.392
• Vapor Pressure: 0.00452mmHg at 25°C
• Refractive Index: 1.5570 (estimate)
• Storage Temp.: 2-8°C
• PKA: 13.69±0.10(Predicted)
• BRN: 3240770
• CAS DataBase Reference: 2,5-DICHLOROBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DICHLOROBENZYL ALCOHOL(34145-05-6)
• EPA Substance Registry System: 2,5-DICHLOROBENZYL ALCOHOL(34145-05-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 34145-05-6(Hazardous Substances Data)

Usage

Chemical Properties

WHITE FINE CRYSTALLINE POWDER

General Description

2,5-Dichlorobenzyl alcohol participates in [Ru(acac)2(CH3CN)2]PF6 (acac = acetylacetone) catalyzed oxidation of alcohols to aldehydes or ketones using H5IO6 as oxidant.

InChI:InChI=1/C7H6Cl2O/c8-6-1-2-7(9)5(3-6)4-10/h1-3,10H,4H2

Upstream product

• 50-79-3 2,5-dichlorobenzoic acid 
• 2905-69-3 methyl 2,5-dichlorobenzoate 
• 100-52-7 benzaldehyde 
• 2745-49-5 1,4-Dichloro-2-chloromethyl-benzene 
• 6361-23-5 2,5-dichloro-benzaldehyde 

Downstream Products

• 5330-38-1 4-chloro-2-hydroxymethylphenol 
• 90273-71-5 Chlor-essigsaeure-(2,5-dichlor-benzylester) 
• 6361-23-5 2,5-dichloro-benzaldehyde 
• 2745-49-5 1,4-Dichloro-2-chloromethyl-benzene 
• 14225-80-0 2-(2,5-dichlorophenyl)-1H-benzo[d]imidazole 
• 1104461-30-4 (2,5-dichloro-phenyl)methyl N-(3-(2,6-dichloro-phenyl)-5-methyl-1,2-oxazol-4-yl)-carbamate 

Relevant articles and documents

Controlled Reduction of Carboxamides to Alcohols or Amines by Zinc Hydrides

New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives amines. Extensive mechanistic studies by experimental and theoretical approaches imply that polymeric zinc hydride (ZnH2)∞ is responsible for alcohol formation, whereas dimeric zinc chloride hydride (H?Zn?Cl)2 is the key species for the production of amines.

Hydrogenation of Esters to Alcohols Catalyzed by Defined Manganese Pincer Complexes

The first manganese-catalyzed hydrogenation of esters to alcohols has been developed. The combination of Mn(CO)5Br with [HN(CH2CH2P(Et)2)2] leads to a mixture of cationic and neutral Mn PNP pincer complexes, which enable the reduction of various ester substrates, including aromatic and aliphatic esters as well as diesters and lactones. Notably, related pincer complexes with isopropyl or cyclohexyl substituents showed very low activity.

Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: 8-substituted 6-(4-piperidyl)-6H-dibenz[b,e]-1,4-oxathiepins

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