341490-01-5

Upstream product

• 100-39-0 benzyl bromide 
• 341489-97-2 1,2:4,5-di-O-isopropylidene-β-D-fructopyranos-3-yl benzyloxyacetate 
• 25018-67-1 1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose 
• 30379-55-6 benzyloxyacetic acid 

Downstream Products

• 182937-63-9 (R)-2-(benzyloxy)-3-phenylpropanoic acid 

Relevant academic research and scientific papers

A highly stereoselective entry to α-hydroxy carboxylic acids using D-fructose diacetonide as a chiral auxiliary

Protected α-hydroxy carboxylic acids were synthesized in moderate yield and high diastereoselectivity by alkylation of glycolate ester enolates using a D-fructose-derived chiral auxiliary. The new chiral center was assigned the (R)-configuration based upon comparisons to the literature. Both enantiomers of the auxiliary are readily available.