3415-07-4Relevant academic research and scientific papers
SYNTHESIS AND TRANSFORMATION OF DERIVATIVES OF THE N- AND O-GLYCOSIDES OF D-RIBOFURANOIC ACID
Timoshchuk, V. A.
, p. 1198 - 1204 (2007/10/02)
A method was developed for the nonselective oxidation of pyrimidine nucleosides and methyl β-D-ribofuranoside to the uronic acids by successive treatment first with triphenylchloromethane and then with acetic anydride in pyridine, followed by oxidation with chromic anhydride in acetone in the presence of sulfuric acid.The transformations of the obtained uronic acids into anhydronucleosides by the action of phthalimide and into 3',4'-unsaturated nucleosides by the action of 1,5-diazabicycloundec-5-ene are described.
