341529-07-5 Usage
Uses
Used in Pharmaceutical Research:
1-(TRIMETHYLSILYLDIFLUOROMETHYL)-1H-IMIDAZOLE is used as a building block in the preparation of various pharmaceuticals and agrochemicals. It is important for the synthesis of antiviral and antifungal agents, as well as in the development of new materials and chemical processes.
Used in Organic Synthesis:
1-(TRIMETHYLSILYLDIFLUOROMETHYL)-1H-IMIDAZOLE is used as a reagent in organic synthesis, enabling the formation of various chemical compounds and facilitating reactions in the synthesis of pharmaceuticals and agrochemicals.
Used in Drug Discovery:
1-(TRIMETHYLSILYLDIFLUOROMETHYL)-1H-IMIDAZOLE is used as a potential candidate in drug discovery due to its unique structure and reactivity, which can contribute to the development of new therapeutic agents.
Used in Medicinal Chemistry:
1-(TRIMETHYLSILYLDIFLUOROMETHYL)-1H-IMIDAZOLE is used in medicinal chemistry for the design and synthesis of new compounds with potential therapeutic applications, particularly in the areas of antiviral and antifungal treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 341529-07-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,1,5,2 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 341529-07:
(8*3)+(7*4)+(6*1)+(5*5)+(4*2)+(3*9)+(2*0)+(1*7)=125
125 % 10 = 5
So 341529-07-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H12F2N2Si/c1-12(2,3)7(8,9)11-5-4-10-6-11/h4-6H,1-3H3
341529-07-5Relevant academic research and scientific papers
Heteroaryl-N-difluoromethyltrimethylsilanes - Versatile sources of heteroaryl-N-difluoromethyl anions in reactions with carbonyl compounds
Bissky,Staninets,Kolomeitsev,R?schenthaler
, p. 374 - 378 (2007/10/03)
An efficient procedure for synthesizing heteroaryl-N-difluoromethyltrimethylsilanes - new nucleophilic difluoromethylene synthons - from easily available N-bromodifluoromethylated heterocycles, chlorotrimethylsilane and aluminium powder in triglyme or N-methylpyrrolidinone on a preparative scale in 71-75% isolated yield is described. Heteroaryl-N-difluoromethyltrimethylsilanes and benzaldehyde react under fluoride ion catalysis to give 1-(1,1-difluor-2-hydroxy-2-phenyl-ethyl)heteroaryls, whereas for anionic heteroaryl-N-difluoromethylation of cyclohexanone a stoichiometrical mixture of heteroaryl-N-difluoromethyltrimethylsilanes and tetramethylammonium fluoride has to be used.
