34153-33-8

Basic information

• Product Name: ethyl 4-(4-nitrophenyl)butanoate
• Synonyms: ethyl 4-(4-nitrophenyl)butanoate
• CAS NO: 34153-33-8
• Molecular Weight: 237.255
• Mol File: 34153-33-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 4-(4-nitrophenyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-nitrophenyl)butanoate(34153-33-8)
• EPA Substance Registry System: ethyl 4-(4-nitrophenyl)butanoate(34153-33-8)

Safety Data

• Hazardous Substances Data: 34153-33-8(Hazardous Substances Data)

Upstream product

• 586-78-7 para-nitrophenyl bromide 
• 64-17-5 ethanol 
• 5600-62-4 4-(4-nitrophenyl)butanoic acid 
• 2969-81-5 Ethyl 4-bromobutyrate 

Downstream Products

• 15116-32-2 4-(4-amino-phenyl)-butyric acid ethyl ester 
• 64977-24-8 ethyl 4-<4'-phenyl>butanoate 
• 305-03-3 chlorambucil 
• 1431791-19-3 2-diazo-6-(4-nitrophenyl)-3-oxohexanenitrile 
• 1431791-95-5 6-(4-nitrophenyl)-3-oxohexanenitrile 

Relevant articles and documents

Purification of fluorous Mitsunobu reactions by liquid-liquid extraction

Solvent tuning and partition coefficient measurements have identified suitable reagent and solvent combinations for the purification of fluorous Mitsunobu reaction products. The crude reaction mixtures are partitioned between 2/1 HFE-7100/FC-72 and DMF/10% water to provide reagent (fluorous) and product (organic) fractions.

α-Diazo-β-ketonitriles: Uniquely reactive substrates for arene and alkene cyclopropanation

An investigation of the intramolecular cyclopropanation reactions of α-diazo-β-ketonitriles is reported. These studies reveal that α-diazo-β-ketonitriles exhibit unique reactivity in their ability to undergo arene cyclopropanation reactions; other similar acceptor-acceptor- substituted diazo substrates instead produce mixtures of C-H insertion and dimerization products. α-Diazo-β-ketonitriles also undergo highly efficient intramolecular cyclopropanation of tri- and tetrasubstituted alkenes. In addition, the α-cyano-α-ketocyclopropane products are demonstrated to serve as substrates for SN2, SN2′, and aldehyde cycloaddition reactions.

Preparation of alkylzinc bromides using a new Mn/Cu catalyzed bromine-zinc exchange reaction

The reaction of functionalized primary alkyl bromides with Et2Zn in DMPU in the presence of a catalytic mixed metal system constituted of MnBr2 (or FeCl3) and CuCl provides functionalyzed alkylzinc bromides (>80% yield). In the presence of PdCl2(dppf) or CuCN-2LiCl, these organozinc species react with a range of electrophiles providing various polyfunctional molecules in good yields.