34155-92-5Relevant academic research and scientific papers
Intermolecular Three-Component Synthesis of Fluorene Derivatives by a Rhodium-Catalyzed Stitching Reaction/Remote Nucleophilic Substitution Sequence
Nishida, Masaki,Lee, Donghyeon,Shintani, Ryo
, p. 8489 - 8500 (2020)
A three-component synthesis of multisubstituted fluorene derivatives has been developed by devising a rhodium-catalyzed stitching reaction/remote nucleophilic substitution sequence. A variety of nucleophiles can be installed in the second step including both heteroatom and carbon nucleophiles. An efficient synthesis of 5H-benzo[a]fluoren-5-ones has also been realized using N-(2-alkynyl)benzoylpyrrole as the reaction partner through a new reaction pathway.
Development of agonists, partial agonists and antagonists in the Δ8- tetrahydrocannabinol series
Crocker,Saha,Ryan,Wiley,Martin,Ross,Pertwee,Razdan
, p. 13907 - 13926 (2007/10/03)
Synthetic sequences were developed (Schemes 1 to 6) for the syntheses of various Δ8-THC analogs with either a rigid acetylenic linkage or a cis- double bond in different positions in the side chain. Various alkyne and cis- ene-Δ8-THC
