34161-43-8Relevant articles and documents
Verdazyl Radical Building Blocks: Synthesis, Structure, and Sonogashira Cross-Coupling Reactions
Petunin, Pavel V.,Martynko, Ekaterina A.,Trusova, Marina E.,Kazantsev, Maxim S.,Rybalova, Tatyana V.,Valiev, Rashid R.,Uvarov, Mikhail N.,Mostovich, Evgeny. A.,Postnikov, Pavel S.
, p. 4802 - 4811 (2018)
A general and effective method for the synthesis of 3-phenylveradzyl radicals bearing a variety of iodophenyl substituents has been developed. The synthesized radicals have been characterized by ESR, UV/Vis spectroscopy, and cyclic voltammetry. Structures of biphenyl-substituted radicals have been solved by X-ray crystal structure analysis. The synthesized iodoverdazyls are applicable in the Sonogashira coupling reaction for the preparation of a wide range of ethynyl derivatives. Both N-2 and C-6 substituents were functionalized through Sonogashira coupling.