34164-94-8

Usage

Structure

Imidazo[1,2-a]pyridine derivative with a 4-chlorophenyl group attached to the imidazole ring

Pharmacological activities

Potential activities of interest in medicinal chemistry research

Applications

May have applications in the development of drugs targeting specific biological pathways or receptors

Value in research

Structure and properties make it a valuable tool for studying structure-activity relationships of related compounds and for designing new chemical entities with desired biological activities.

Further research needed

To fully understand the potential uses and properties of the compound.

Upstream product

• 601468-08-0 N?(tert?butyl)?2?(4?chlorophenyl)imidazo[1,2?a]pyridin?3?amine 
• 1323381-60-7 N-(4-chlorobenzylidene)[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]amine 
• 504-29-0 2-aminopyridine 
• 104-88-1 4-chlorobenzaldehyde 
• 119072-55-8 tert-butylisonitrile 
• 859359-24-3 N-2-(2,4,4-trimethylpentan-2-yl) 2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-amine 

Relevant academic research and scientific papers

Skeletal diverse synthesis of N-fused polycyclic heterocycles via the sequence of Ugi-type MCR and CuI-catalyzed coupling/tandem Pictet-Spengler reaction

Several diversity-oriented syntheses of N-fused polycyclic heterocycles have been demonstrated but most of them are based on point diversity within the same library and usually involve time-consuming sequential multistep syntheses, which also suffer from

(Bromodimethylsulfonium) bromide-catalyzed one-pot three-component synthesis of imidazo[1,2-a]pyridines

Figure represented. (Bromodimethylsulfonium) bromide-catalyzed one-pot multicomponent reaction of 2-aminopyridine with aromatic aldehyde(s) and TMSCN yielding N-benzylidene-2-phenylimidazo[1,2-a]pyridines exclusively has been described. The reaction is so

N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase

On the basis of structures of known topoisomerase II catalytic inhibitors and initial molecular docking studies, bicyclic N-fused aminoimidazoles were predicted as potential topoisomerase II inihibitors. They were synthesized by multicomponent reactions a

Towards molecular diversity: Dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile

With the development of a novel microwave-assisted one-pot tandem de-tert-butylation of tert-butyl amine in an Ugi-type multicomponent reaction product, tert-butyl isocyanide as a useful convertible isonitrile has been explored for the first time affordin

An efficient, regioselective, versatile synthesis of N-fused 2- and 3-aminoimidazoles via Ugi-type multicomponent reaction mediated by zirconium(IV) chloride in polyethylene glycol-400

An Ugi-type multicomponent reaction of heterocyclic amidines with aldehydes and isocyanides catalyzed by zirconium(IV) chloride in PEG-400 was developed. The protocol offers the rapid, environment friendly, regioselective and versatile synthesis of medici