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3-nitro-5-methylimidazo[1,2-a]pyridine (N-MeIQ) is a heterocyclic aromatic amine compound that is formed during the cooking of meat at high temperatures, such as grilling or frying. It is a potent mutagen and carcinogen, classified as a Group 2B carcinogen by the International Agency for Research on Cancer, indicating its potential carcinogenicity to humans. N-MeIQ has been shown to induce tumors in various organs, including the colon, liver, and lung, in animal studies.

34165-08-7

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34165-08-7 Usage

Uses

Used in Research and Toxicology Studies:
3-nitro-5-methylimidazo[1,2-a]pyridine is used as a model compound in research and toxicology studies to investigate the mechanisms of carcinogenesis and mutagenicity associated with dietary exposure to heterocyclic aromatic amines. It helps scientists understand the potential health risks posed by these compounds and develop strategies to minimize their formation and consumption in cooked meat products.
Used in Food Safety and Quality Control:
3-nitro-5-methylimidazo[1,2-a]pyridine is used as an indicator in food safety and quality control to monitor the presence of heterocyclic aromatic amines in cooked meat products. Analytical methods, such as high-performance liquid chromatography (HPLC) and mass spectrometry, are employed to detect and quantify N-MeIQ levels, ensuring compliance with safety standards and minimizing the risk of cancer associated with dietary exposure to this chemical.
Used in Public Health and Risk Assessment:
3-nitro-5-methylimidazo[1,2-a]pyridine is used in public health and risk assessment to evaluate the potential impact of dietary exposure to heterocyclic aromatic amines on human health. Epidemiological studies and risk assessments are conducted to estimate the levels of exposure to N-MeIQ and other related compounds, providing insights into the need for regulatory measures and consumer education to reduce the risk of cancer associated with the consumption of cooked meat products.

Check Digit Verification of cas no

The CAS Registry Mumber 34165-08-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,1,6 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 34165-08:
(7*3)+(6*4)+(5*1)+(4*6)+(3*5)+(2*0)+(1*8)=97
97 % 10 = 7
So 34165-08-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7N3O2/c1-6-3-2-4-7-9-5-8(10(6)7)11(12)13/h2-5H,1H3

34165-08-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-3-nitroimidazo[1,2-a]pyridine

1.2 Other means of identification

Product number -
Other names 5-methyl-3-nitro-imidazo[1,2-a]pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:34165-08-7 SDS

34165-08-7Relevant academic research and scientific papers

Reactions with N-chlorosuccinimide of various 5-methylimidazo[1,2-a]pyridine derivatives with an electron-withdrawing group substituted at the 3-position

Ikemoto, Tomomi,Wakimasu, Mitsuhiro

, p. 99 - 108 (2007/10/03)

Chlorination reactions using N-chlorosuccinimide (NCS) was investigated for various 5-methylimidazo[1,2-a]pyridine derivatives with an electron-withdrawing group substituted at the 3-position. These reactions showed different results, and by examining these, we proposed a reaction mechanism via the appropriate 3-halogenoimidazo[1,2-a]pyridium compounds as the reaction intermediates.

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