34165-08-7 Usage
General Description
3-nitro-5-methylimidazo[1,2-a]pyridine (N-MeIQ) is a chemical compound that belongs to the class of heterocyclic aromatic amines. It is a potent mutagen and carcinogen that is formed during the cooking of meat at high temperatures, such as grilling or frying. N-MeIQ is classified as a Group 2B carcinogen by the International Agency for Research on Cancer, meaning that it is possibly carcinogenic to humans. It has been shown to induce tumors in various organs, including the colon, liver, and lung, in animal studies. The presence of N-MeIQ in cooked meat products poses a potential health risk, and efforts to minimize its formation and consumption are important for reducing the risk of cancer associated with dietary exposure to this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 34165-08-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,1,6 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 34165-08:
(7*3)+(6*4)+(5*1)+(4*6)+(3*5)+(2*0)+(1*8)=97
97 % 10 = 7
So 34165-08-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7N3O2/c1-6-3-2-4-7-9-5-8(10(6)7)11(12)13/h2-5H,1H3
34165-08-7Relevant articles and documents
Reactions with N-chlorosuccinimide of various 5-methylimidazo[1,2-a]pyridine derivatives with an electron-withdrawing group substituted at the 3-position
Ikemoto, Tomomi,Wakimasu, Mitsuhiro
, p. 99 - 108 (2007/10/03)
Chlorination reactions using N-chlorosuccinimide (NCS) was investigated for various 5-methylimidazo[1,2-a]pyridine derivatives with an electron-withdrawing group substituted at the 3-position. These reactions showed different results, and by examining these, we proposed a reaction mechanism via the appropriate 3-halogenoimidazo[1,2-a]pyridium compounds as the reaction intermediates.
