34203-25-3

Usage

Uses

Used in Pharmaceutical Industry:
Thiazole, 2-iodo-4-methyl-, is used as a building block in the synthesis of various biologically active compounds for the pharmaceutical industry. Its unique chemical properties contribute to the development of potential anti-cancer, anti-inflammatory, and antimicrobial agents, offering new therapeutic options for various diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical industry, Thiazole, 2-iodo-4-methyl-, serves as an intermediate in the production of various agrochemicals. Its potential applications in this field include the development of new pesticides, herbicides, and other agricultural chemicals that can improve crop protection and yield.
Used in Materials Science:
Thiazole, 2-iodo-4-methyl-, is utilized in materials science for the development of functional materials with specific properties. Its unique chemical structure allows for the creation of materials with tailored characteristics, such as improved stability, reactivity, or selectivity, which can be applied in various industrial processes and technologies.

Upstream product

• 7553-56-2 iodine 
• 693-95-8 4-Methylthiazole 

Downstream Products

• 40615-11-0 1-(4-methyl-thiazol-2-yl)-piperazine 
• 1614251-47-6 3-(1,3-dimethyl-10-(4-methylthiazol-2-yl)-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[4,5-a]indolizin-5-yl)benzonitrile 
• 1614252-57-1 1,3-dimethyl-10-(4-methylthiazol-2-yl)-5-m-tolyl-7,8-dihydropyrimido[4,5-a]indolizine-2,4(1H,3H)-dione 

Relevant academic research and scientific papers

Molecular diodes based on conjugated diblock co-oligomers

This report describes synthesis and characterization of a molecular diode based upon a diblock conjugated oligomer system. This system consists of two conjugated blocks with opposite electronic demand. The molecular structure exhibits a built-in electronic asymmetry, much like a semiconductor p-n junction. Electrical measurements by scanning tunneling spectroscopy (STS) clearly revealed a pronounced rectifying effect. Definitive proof for the molecular nature of the rectifying effect in this conjugated diblock molecule is provided by control experiments with a structurally similar reference compound. Copyright

TRICYCLIC COMPOUNDS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

TRICYCLIC COMPOUNDS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

LXR AND FXR MODULATORS

Compounds of the invention are disclosed, such as compounds of formulae LX - LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R00, R200, R400, R500, J11, J21, G1, G21, and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.

[4-(HETEROARYL) PIPERAZIN-1-YL]-(2,5-SUBSTITUTED -PHENYL)METHANONE DERIVATIVES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS

The present invention relates to compounds of the general formula (I) wherein R1 is-OR1’,-SR1’ or is a heterocycloalkyl group; R1’ is lower alkyl, lower alkyl substituted by halogen or is -(CH2)n

Remarkable synthesis of 2-(Z)-6-(E)-4H- [1,4]-thiazepin-5-ones by zwitterionic rhodium-catalyzed chemo- and regioselective cyclohydrocarbonylative ring expansion of acetylenic thiazoles

Cyclohydrocarbonylative ring expansion of acetylenic thiazoles in the presence of CO, H2, and catalytic quantities of the zwitterionic rhodium complex η6-C6H5BPh3) -Rh+(1,5-COD) and triphenyl phosphite affords thiazepinones in 61 to 90% yields. This novel transformation of a 5- to a 7-membered heterocycle is readily applied to acetylenic thiazoles containing hydro, alkyl, alkyl halide, vinyl, and benzo substitutents in positions 4 and 5 of the thiazole ring in addition to alkyl-, ether-, ester-, vinyl-, and aryl-substituted alkynes at position 2.