34227-83-3Relevant articles and documents
PROCESS FOR PREPARING SPHINGOLIPIDS
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Paragraph 0108; 0112, (2019/10/23)
The invention provides a process for preparing sphingolipids, compositions comprising sphingolipids and further components, and for the use of the compositions.
Method of making primary amide derivative
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, (2008/06/13)
A method of selective N-acylation of an aminodiol having a primary alcoholic hydroxyl group and a secondary alcoholic hydroxyl group, in which the objective product can be prepared in high yield and without troublesome extraction and purification operations. More particularly, a method of making a primary amide derivative represented by the following general formula (3) is disclosed: STR1 wherein R1 represents a linear saturated aliphatic hydrocarbon group having 11 to 19 carbon atoms, R2 represents a linear saturated or unsaturated aliphatic hydrocarbon group having 9 to 19 carbon atoms which may have a hydroxyl group at the 1-position, which includes the steps of reacting an aminodiol represented by the following general formula (1): STR2 wherein R1 is the same as R1 in general formula (3) with a fatty acid alkyl ester represented by the following general formula (2): wherein R2 is the same as R2 in general formula (3) and R3 represents a lower alkyl group, in a reaction system comprising an alcoholic solvent and in the presence of a basic catalyst, said reacting step forming a lower alcohol as a by-product; and removing the lower alcohol formed during the reaction from the reaction system.
