34227-83-3

Usage

Uses

Used in Pharmaceutical Industry:
N-oleoyl-D-erythro-sphinganine is used as a bioactive compound for its potential therapeutic effects. It has been found to modulate various cellular signaling pathways and may have implications in the treatment of certain diseases, including cancer.
Used in Cosmetic Industry:
In the cosmetic industry, N-oleoyl-D-erythro-sphinganine is used as an ingredient in skincare products for its moisturizing and skin barrier strengthening properties. It helps to maintain the skin's natural moisture balance and may contribute to a smoother and more supple skin texture.
Used in Research Applications:
N-oleoyl-D-erythro-sphinganine is also used as a research tool in the study of lipid metabolism, cell signaling, and the role of ceramide in various biological processes. It can be employed in experimental setups to investigate the effects of this specific dihydroceramide on cell function and behavior.

InChI:InChI=1/C36H71NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,34-35,38-39H,3-16,19-33H2,1-2H3,(H,37,40)/b18-17-/t34-,35+/m0/s1

Upstream product

• 764-22-7 (2S,3R)-2-amino-1,3-octadecanediol 
• 5938-38-5 sorbitan monooleate 
• 112-77-6 (Z)-9-octadecenoyl chloride 

Relevant academic research and scientific papers

PROCESS FOR PREPARING SPHINGOLIPIDS

The invention provides a process for preparing sphingolipids, compositions comprising sphingolipids and further components, and for the use of the compositions.

The synthesis and biological characterization of a ceramide library

A facile synthesis of a combinatorial ceramide library and their activities in the NF-κB pathway and in apoptosis induction/prevention were demonstrated. A novel NF-κB activating molecule was discovered among ceramide containing β-galactose, and the structural requirements of ceramides for apoptosis induction was elucidated. Copyright

Method of making primary amide derivative

A method of selective N-acylation of an aminodiol having a primary alcoholic hydroxyl group and a secondary alcoholic hydroxyl group, in which the objective product can be prepared in high yield and without troublesome extraction and purification operations. More particularly, a method of making a primary amide derivative represented by the following general formula (3) is disclosed: STR1 wherein R1 represents a linear saturated aliphatic hydrocarbon group having 11 to 19 carbon atoms, R2 represents a linear saturated or unsaturated aliphatic hydrocarbon group having 9 to 19 carbon atoms which may have a hydroxyl group at the 1-position, which includes the steps of reacting an aminodiol represented by the following general formula (1): STR2 wherein R1 is the same as R1 in general formula (3) with a fatty acid alkyl ester represented by the following general formula (2): wherein R2 is the same as R2 in general formula (3) and R3 represents a lower alkyl group, in a reaction system comprising an alcoholic solvent and in the presence of a basic catalyst, said reacting step forming a lower alcohol as a by-product; and removing the lower alcohol formed during the reaction from the reaction system.