34236-68-5Relevant academic research and scientific papers
Asymmetric Hydrogenation of Racemic Allylic Alcohols via an Isomerization-Dynamic Kinetic Resolution Cascade
Guo, Xin,Niu, Saisai,Sun, Huaming,Tang, Weijun,Wang, Chao,Wang, Kun,Xiao, Jianliang,Xue, Dong
supporting information, (2022/02/05)
Prochiral racemic allylic alcohols are converted to enantioenriched chiral alcohols bearing adjacent stereocenters catalyzed by a diamine diphosphine Ru complex in the presence of tBuOK. The protocol features a broad substrate scope (56 examples) and high
Stereodivergent Access to Enantioenriched Epoxy Alcohols with Three Stereogenic Centers via Ruthenium-Catalyzed Transfer Hydrogenation
Zhao, Zhifei,Bagdi, Prasanta Ray,Yang, Shuang,Liu, Jinggong,Xu, Weici,Fang, Xinqiang
supporting information, p. 5491 - 5494 (2019/08/01)
The resolution technique of stereodivergent reaction on racemic mixtures (stereodivergent RRM) was employed for the first time in ruthenium complex catalyzed transfer hydrogenation of racemic epoxy ketones, providing a new and very simple method that allows access to enantioenriched epoxy alcohols with three stereogenic centers in a one-step fashion. The protocol features simple reaction conditions, practical operation, ability to scale up, and broad group tolerance.
Synthesis and reactivity of dioxazirconacyclohexenes: Development of a zirconium-oxo-mediated alkyne-aldehyde coupling reaction
Kortman, Gregory D.,Orr, Meghan J.,Hull, Kami L.
supporting information, p. 1013 - 1016 (2015/03/31)
The zirconium-oxo-mediated coupling of an alkyne and an aldehyde for the synthesis of α,β-unsaturated ketones is presented. Each intermediate along the reaction pathway has been fully characterized, and the scope of the alkynes and aldehydes has been explored.
