342406-53-5Relevant academic research and scientific papers
Selective amidation by a photocatalyzed umpolung reaction
Ghosh, Debasish,Nandi, Rajesh,Khamarui, Saikat,Ghosh, Sukla,Maiti, Dilip K.
, p. 3883 - 3886 (2019)
A metal-catalyzed organic transformation merged with another organophotocatalyst has been developed under mild conditions for production of α-ketoamides. CuI-catalyzed highly selective and rapid COCH2-amidation in the presence of electrophilic CαO bonds, which is synchronized by an eosin Y (EY)-photocatalyst, furnishes a wide range of labile α-ketoamides, unsymmetrical oxalamides and chiral analogues on the treatment of 1,3-dicarbonyls with amines, PhIO and LED light at room temperature. The current strategy opens up a new avenue to making photocatalysis a common synthetic tool for large-scale production in academia and industry.
Synthesis of 1,3-Disubstituted Diazolidines
Lambert, Joseph B.,Huseland, Dave E.,Wang, Gen-tai
, p. 657 - 658 (2007/10/02)
Symmetrical and unsymmetrical 1,3-diaminoethanes 1 are obtained by the reduction of N,N'-disubstituted oxamides 4 with lithium aluminum hydride.The oxamides 4 are readily produced by treatment of diethyl oxalate with primary amines.The 1,3-diaminoethanes 1 lead to 1,3-diazolidines 2 on treatment with formaldehyde.
