342422-63-3Relevant academic research and scientific papers
The stereochemistry of organometallic compounds XXXVI. Rhodium-catalysed reactions of unsaturated amines with hydrogen and carbon monoxide. A new synthesis of 2-piperidinones
Anastasiou, Despina,Jackson, W. Roy
, p. 399 - 410 (1991)
Rhodium-catalysed reactions of 5-aminopent-1-enes with carbon monoxide and hydrogen give 2-piperidinone derivatives in high yields under mild conditions.Reaction of allylamine under similar conditions gave exclusively 2-pyrrolidone in high yield and reactions of 4-aminobut-1-enes gave mixtures of 2-piperidinones and 2-pyrrolidinones.The role of the hydrogen in these reactions is discussed.
