34243-10-2 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
The compound belongs to the oxadiazole family, which is a group of five-membered heterocycles containing two nitrogen atoms and one oxygen or sulfur atom.
Explanation
The compound contains a thione group (C=S), which is a carbon-sulfur double bond. This group is responsible for some of its potential applications in pharmaceuticals and materials science.
Explanation
The compound is synthesized through a chemical reaction between 4-methylphenol and thiosemicarbazide, which are the starting materials.
Explanation
The compound exists as a solid in its pure form, which is a common state for many organic compounds.
Explanation
The compound has been found to exhibit potential biological activities, such as antimicrobial (fighting against microorganisms) and anti-inflammatory (reducing inflammation) properties.
Explanation
Due to its thione group and biological activities, the compound may have potential applications in the development of new pharmaceuticals and materials with specific properties.
Explanation
The presence of oxygen and sulfur atoms in the compound suggests that it may act as a ligand in coordination chemistry, which involves the study of metal complexes with ligands.
Explanation
The compound's properties and potential applications make it a versatile compound, with the possibility of being used in different fields such as pharmaceuticals, materials science, and coordination chemistry.
Family
Oxadiazole
Thione group
Present
Synthesis
Reaction of 4-methylphenol and thiosemicarbazide
Physical state
Organic solid
Biological activities
Antimicrobial and anti-inflammatory properties
Potential applications
Pharmaceuticals and materials science
Coordination chemistry
Possible ligand
Versatility
Various fields of application
Check Digit Verification of cas no
The CAS Registry Mumber 34243-10-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,2,4 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 34243-10:
(7*3)+(6*4)+(5*2)+(4*4)+(3*3)+(2*1)+(1*0)=82
82 % 10 = 2
So 34243-10-2 is a valid CAS Registry Number.
34243-10-2Relevant academic research and scientific papers
Expedient discovery for novel antifungal leads: 1,3,4-Oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment
Wang, Xiaobin,Chai, Jianqi,Kong, Xiangyi,Jin, Fei,Chen, Min,Yang, Chunlong,Xue, Wei
, (2021/08/03)
Developing novel fungicide candidates are intensively promoted by the rapid emergences of resistant fungi that outbreak on agricultural production. Aiming to discovery novel antifungal leads, a series of 1,3,4-oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment were constructed for evaluating their inhibition effects against phytopathogenic fungi in vitro and in vivo. Systematically structural optimizations generated the bioactive molecule I32 that was identified as a promising inhibitor against Rhizoctonia solani with the in vivo preventative effect of 58.63% at 200 μg/mL. The observations that were captured by scanning electron microscopy and transmission electron microscopy demonstrated that the bioactive molecule I32 could induce the sprawling growth of hyphae, the local shrinkage and rupture on hyphal surfaces, the extreme swelling of vacuoles, the striking distortions on cell walls, and the reduction of mitochondria numbers. The above results provided an indispensable complement for the discovery of antifungal lead bearing a quinazolin-4(3H)-one and 1,3,4-oxadiazole fragment.
2,5-substituent-1,3,4-oxadiazole (thiadiazole) thioether derivatives as well as preparation method and application thereof
-
, (2017/04/03)
The invention discloses 2,5-substituent-1,3,4-oxadiazole (thiadiazole) thioether derivatives as well as a preparation method and an application thereof. The 2,5-substituent-1,3,4-oxadiazole (thiadiazole) thioether derivatives have the general formula (I) shown in the following specification, wherein R1 represents as 4-chlorphenyl, 4-fluorophenyl, 4-methylphenyl, 4-methoxyphenyl, 4-nitrophenyl, 4-cyano-3,5-difluorophenyl, 4-trifluoromethylphenyl, 4-trifluoromethoxyphenyl, 4-t-butylphenyl, 2-fluorophenyl and other substituents; R2 represents methyl, ethyl, 4-chlorobenzyl, 2,4-dichlorobenzyl, 4-trifluoromethoxy, benzyl, 4-fluorobenzyl, 4-chlorobenzyl and other substituents; X represents O or S. The compound can be used as a pesticide for killing crop nematode and inhibiting bacterial diseases of crops.
