3425-99-8

Usage

Uses

Used in Pharmaceutical Production:
(1,2-dibromo-2-nitroethyl)benzene serves as a crucial intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a building block for the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Pesticide Formulation:
In agriculture, (1,2-dibromo-2-nitroethyl)benzene is utilized in the production of pesticides. Its chemical properties make it effective in controlling pests, thereby protecting crops and ensuring food security.
Used in Dye Manufacturing:
(1,2-dibromo-2-nitroethyl)benzene also finds application in the dye industry, where it is used in the creation of various dyes. Its ability to impart color makes it a valuable component in the formulation of dyes for different applications, including textiles and other industrial uses.
Used as an Intermediate in Organic Synthesis:
Beyond its direct applications, (1,2-dibromo-2-nitroethyl)benzene is also employed as an intermediate in the synthesis of other organic compounds. Its reactivity and functional groups make it a useful precursor in organic chemistry for creating a wide array of products.
Used in Chemical Research:
In the realm of scientific research, (1,2-dibromo-2-nitroethyl)benzene is utilized in various chemical studies to explore new reactions and understand the behavior of organic compounds under different conditions, thus contributing to the broader field of chemistry.
Given the hazardous nature of (1,2-dibromo-2-nitroethyl)benzene, it is imperative that all safety guidelines are adhered to during its handling, storage, and use to minimize risks to human health and the environment.

Upstream product

• 5153-67-3 nitrostyrene 
• 103-64-0 bromostyrene 
• 102-96-5 (2-nitroethenyl)benzene 

Downstream Products

• 5153-67-3 nitrostyrene 
• 60456-19-1 (2-bromo-2-nitro-1-phenyl-ethyl)-methyl ether 
• 18315-81-6 (Z)-2-bromo-2-nitro-1-phenylethene 
• 64-04-0 phenethylamine 
• 98995-93-8 2-methoxy-2-phenylacetaldoxime 
• 7166-19-0 (2-bromo-2-nitroethenyl)benzene 
• 80-48-8 methyl p-toluene sulfonate 
• 102-96-5 (2-nitroethenyl)benzene 
• 1071-86-9 bis(formamidine)disulphide dihydrobromide 
• 103-19-5 di(p-tolyl) disulfide 
• 19190-53-5 2-methoxy-2-phenylacetaldehyde 

Relevant academic research and scientific papers

Electrochemical bromination of cyclic and acyclic enes using biphasic electrolysis

A simple method of electrochemical bromination of a series of cyclic and acyclic enes (styrene and substituted styrenes, stilbene, indene, and cyclooctene) in a biphasic water-chloroform mixture mediated by bromide/bromine redox system is reported. Aqueous 25% NaBr/H2SO4 is used as the electrolyte. Regio- and stereoselective dibromination of enes is achieved. Moderate to excellent yields of the product (83-98%) is obtained depending on the substrate. Electrolyte reuse has also been demonstrated successfully using HBr in the dibromination of styrene.

Novel synthesis scheme and in vitro antimicrobial evaluation of a panel of (E)-2-aryl-1-cyano-1-nitroethenes

Drug resistance has become a major concern in the field of infection management, therefore searching for new antibacterial agents is getting more challenging. Our study presents an optimized and eco-friendly synthesis scheme for a panel of nitroalkenes be

Halocarbocyclization versus dihalogenation: Substituent directed iodine(iii) catalyzed halogenations

The nucleophilicity of the substituents in iodobenzene pre-catalysts have a huge impact on product selectivity in iodine(iii) triggered halogenations, steering the reactivity from solely carbocyclizations towards dihalogenations. Utilizing this catalyst-dependent reactivity a diastereo- and chemoselective dihalogenation method was established allowing the conversion of structurally and electronically diverse unsaturated compounds in excellent yields.

Organocatalysis as a safe practical method for the stereospecific dibromination of unsaturated compounds

Organocatalytic stereospecific dibromination of a wide variety of functionalized alkenes was achieved using a stable, inexpensive halogen source, 1,3-dibromo 5,5-dimethylhydantoin, and a simple thiourea catalyst at room temperature. The presence of a tertiary amine enhanced the rate of the dibromination reaction, and yields were good in various solvents, including aqueous solvents. The procedure was extended to alkynes and aromatic rings and to dichlorination reactions by using the 1,3-dichloro hydantoin derivative.

Simple and practical halogenation of arenes, alkenes and alkynes with hydrohalic acid/H2O2 or TBHP)

A simple protocol for the halogenation of arenes utilizing a combination of aqueous hydrogen peroxide (34 %) or tert-butylhydroperoxide (70 %) and hydrohalic acid is presented. A similar procure of oxyhalogenation involving the in situ generation of positive halogen reagents is applied for the preparation of vicinal trans-dibromoalkanes and dichloroalkanes from alkenes. The reaction of alkenes with a combination of hydrochloric acid and hydrobromic acid with hydrogen peroxide gave a mixture of 1-bromo 2-chloro alkanes and 1,2-dibromoalkanes: Oxidative bromination of alkynes is also reported under similar conditions.

Aqueous isothiazolone formulation

An aqueous isothiazolone formulation useful for antiseptic or antifungal treatment of various synthetic polymeric emulsions, which comprises (a) a specific isothiazolone compound, (b) water or an aqueous solvent and (c) a specific nitrobromo or cyanobromo compound.

Research on antitumor chemotherapy: X. β Nitrostyrene and nitrovinyl derivatives

In previous work, the antitumoral cytotoxicity of β nitrostyrenes obtained by simplification of the aristolochic acid molecule was demonstrated. The effect of modifying the 3 characteristic parts of the β nitrostyrene molecule was then investigated. Results in vitro and in vivo indicate a probable mechanism of action for the β nitrostyrene and nitrovinyl compounds studied, and permit definition of the maximum simplification compatible with retention of biological activity.